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Combined lowering o...
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Siegel, GünterUppsala universitet,Institutionen för farmaci
(author)
Combined lowering of low grade systemic inflammation and insulin resistance in metabolic syndrome patients treated with Ginkgo biloba
- Article/chapterEnglish2014
Publisher, publication year, extent ...
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Elsevier BV,2014
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:uu-241413
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-241413URI
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https://doi.org/10.1016/j.atherosclerosis.2014.10.023DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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In a clinical pilot study with eleven metabolic syndrome patients, a simultaneous decrease in hs-CRP from 8.85 +/- 4.09 to 4.92 +/- 2.51 mg/L (-44.4%) (p < 0.0436) and HOMA-IR from 3.07 +/- 0.63 to 2.60 +/- 0.51 mU/L x mg/dL (-15.3%) (p < 0.0120) as well as a beneficial change of arteriosclerotic, inflammatory and oxidative stress biomarkers were detected after 2-month treatment with Ginkgo biloba. Furthermore, both IL-6 (-12.9%, p < 0.0407) and nanoplaque formation (-14.3%, p < 0.0077) were additionally reduced. According to a large clinical trial elucidating the importance of insulin resistance and low-grade systemic inflammation for cardiovascular disease and overall mortality risk, these data might indicate a CVD/total mortality risk reduction.
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Ermilov, E.
(author)
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Knes, O.
(author)
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Rodriguez, M.
(author)
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Uppsala universitetInstitutionen för farmaci
(creator_code:org_t)
Related titles
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In:Atherosclerosis: Elsevier BV237:2, s. 584-5880021-91501879-1484
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