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Halogenated Dodecab...
Halogenated Dodecaborate Clusters as Agents to Trigger Release of Liposomal Contents
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- Awad, Doaa (author)
- Department of Biochemistry, Alexandria University, Egypt AND Department of Chemistry, University of Bremen, Germany AND Jacobs University Bremen, Germany
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- Bartok, Melinda (author)
- Department of Chemistry, University of Bremen, Germany AND Jacobs University Bremen, Germany
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- Mostaghimi, Farzin (author)
- Department of Chemistry, University of Bremen, Germany
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- Schrader, Imke (author)
- Department of Chemistry, University of Bremen, Germany
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- Sudumbrekar, Neeti (author)
- Department of Chemistry, University of Bremen, Germany
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- Schaffran, Tanja (author)
- Department of Chemistry, University of Bremen, Germany
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- Jenne, Carsten (author)
- Fachbereich C–Anorganische Chemie, Bergische Universit!t Wuppertal, Germany
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- Eriksson, Jonny (author)
- Uppsala universitet,Analytisk kemi
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- Winterhalter, Mathias (author)
- Jacobs University Bremen, Germany
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- Fritz, Jürgen (author)
- Jacobs University Bremen, Germany
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- Edwards, Katarina (author)
- Uppsala universitet,Analytisk kemi
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- Gabel, Detlef (author)
- Department of Chemistry, University of Bremen, Germany AND Jacobs University Bremen, Germany
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(creator_code:org_t)
- 2015-01-12
- 2015
- English.
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In: ChemPlusChem. - : Wiley. - 2192-6506. ; 80:4, s. 656-664
- Related links:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Halogenated dodecaborates, and especially dodecaiodododecaborate(2−), are found to trigger effectively the release of the contents of phospholipid liposomes, including liposomes containing distearoylphosphatidylcholine and cholesterol, which are used clinically in cancer therapy. The basis of the release is studied through differential scanning calorimetry, cryo-transmission electron microscopy, and atomic force microscopy. Upon administration at high concentrations, drastic morphological changes are induced by the dodecaborates. Their possible use in triggered release is suggested.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Keyword
- boron
- cluster compounds
- cryo-transmission electron microscopy
- differential scanning calorimetry
- liposomes
- triggered release
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Awad, Doaa
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Bartok, Melinda
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Mostaghimi, Farz ...
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Schrader, Imke
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Sudumbrekar, Nee ...
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Schaffran, Tanja
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Jenne, Carsten
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Eriksson, Jonny
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Winterhalter, Ma ...
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Fritz, Jürgen
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Edwards, Katarin ...
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Gabel, Detlef
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
- Articles in the publication
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ChemPlusChem
- By the university
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Uppsala University