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A path forward in t...
A path forward in the debate over health impacts of endocrine disrupting chemicals
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Zoeller, R. Thomas (author)
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- Bergman, Ake (author)
- Karolinska Institutet
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Becher, Georg (author)
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Bjerregaard, Poul (author)
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Bornman, Riana (author)
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- Brandt, Ingvar (author)
- Uppsala universitet,Miljötoxikologi
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Iguchi, Taisen (author)
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Jobling, Susan (author)
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Kidd, Karen A. (author)
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Kortenkamp, Andreas (author)
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Skakkebaek, Niels E. (author)
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Toppari, Jorma (author)
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Vandenberg, Laura N. (author)
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(creator_code:org_t)
- 2014
- 2014
- English.
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In: Environmental Health. - 1476-069X. ; 13, s. 118-
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Several recent publications reflect debate on the issue of "endocrine disrupting chemicals" (EDCs), indicating that two seemingly mutually exclusive perspectives are being articulated separately and independently. Considering this, a group of scientists with expertise in basic science, medicine and risk assessment reviewed the various aspects of the debate to identify the most significant areas of dispute and to propose a path forward. We identified four areas of debate. The first is about the definitions for terms such as "endocrine disrupting chemical", "adverse effects", and "endocrine system". The second is focused on elements of hormone action including "potency", "endpoints", "timing", "dose" and "thresholds". The third addresses the information needed to establish sufficient evidence of harm. Finally, the fourth focuses on the need to develop and the characteristics of transparent, systematic methods to review the EDC literature. Herein we identify areas of general consensus and propose resolutions for these four areas that would allow the field to move beyond the current and, in our opinion, ineffective debate.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- Endocrine disruptor
- UNEP
- WHO
- State of the science
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Zoeller, R. Thom ...
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Bergman, Ake
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Becher, Georg
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Bjerregaard, Pou ...
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Bornman, Riana
-
Brandt, Ingvar
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show more...
-
Iguchi, Taisen
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Jobling, Susan
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Kidd, Karen A.
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Kortenkamp, Andr ...
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Skakkebaek, Niel ...
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Toppari, Jorma
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Vandenberg, Laur ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
- Articles in the publication
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Environmental He ...
- By the university
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Uppsala University
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Karolinska Institutet