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Near infrared radia...
Near infrared radiation damage mechanism in the lens
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- Söderberg, Per G. (author)
- Uppsala universitet,Oftalmiatrik
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- Talebizadeh, Nooshin (author)
- Uppsala universitet,Oftalmiatrik
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- Galichanin, Konstantin (author)
- Uppsala universitet,Oftalmiatrik
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- Kronschläger, Martin (author)
- Uppsala universitet,Oftalmiatrik
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Schulmeister, Karl (author)
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- Yu, Zhaohua (author)
- Uppsala universitet,Oftalmiatrik
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(creator_code:org_t)
- SPIE, 2015
- 2015
- English.
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In: OPHTHALMIC TECHNOLOGIES XXV. - : SPIE. - 9781628413977
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- The current data strongly indicates that there is no photochemical effect of in vivo exposure to 1090 nm near IRR radiation within the pupil. Four groups of 20 Sprague-Dawley rats were unilaterally exposed in vivo to 96 W.cm(-2) centered inside the pupil for 10, 18, 33 and 60 min, respectively depending on group belonging. This resulted in radiant exposure doses of 57, 103, 198 and 344 kJ.cm(-2). Temperature evolution at the limbus during the exposure and difference of intensity of forward light scattering between the exposed and the contralateral not exposed eye was measured at 1 week after exposure. The temperature at the limbus was found to increase exponentially towards an asymptote with an asymptote temperature of around 7 degrees C and a time constant (1/k) of around 15 s. No increase of light scattering was found despite that the cumulated radiant exposure dose was [80; 250] times the threshold for photochemically induced cataract suggested by previous empirical data. It is concluded that at 1090 nm near IRR there is no photochemical effect.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Keyword
- near infrared radiation
- cataract
- in vivo
- photochemical
- thermal
Publication and Content Type
- ref (subject category)
- kon (subject category)
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