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Kick-starting the c...
Kick-starting the cancer-immunity cycle by targeting CD40
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- Ellmark, Peter (author)
- Lund University,Lunds universitet,Institutionen för immunteknologi,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Immunotechnology,Departments at LTH,Faculty of Engineering, LTH,Alligator Biosciences AB
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- Mangsbo, Sara M. (author)
- Uppsala universitet,Klinisk immunologi
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Furebring, C. (author)
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- Tötterman, Thomas H. (author)
- Uppsala universitet,Klinisk immunologi
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Norlen, P. (author)
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(creator_code:org_t)
- 2015
- 2015
- English.
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In: Oncoimmunology. - 2162-4011 .- 2162-402X. ; 4:7
- Related links:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Subject headings
Close
- Stimulation of CD40 on dendritic cells to expand and activate tumor-specific T cells and generate anticancer immunity is an attractive therapeutic approach. Since CD40 agonists exert their effects upstream of checkpoint inhibitors, including PD-1 or PD-L1 antagonists, they are ideal candidates for combination regimens.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- CD40
- PD-1
- agonistic antibody
- immunooncology
- CD40
- PD-1
- agonistic antibody
- immunooncology
Publication and Content Type
- vet (subject category)
- art (subject category)
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