Search: onr:"swepub:oai:DiVA.org:uu-265473" >
Complement activati...
Complement activation by polymethyl methacrylate minimized by end-point heparin attachment.
-
Pekna, M (author)
-
Larsson, R (author)
-
Formgren, B (author)
-
show more...
-
- Nilsson, U R (author)
- Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi
-
- Nilsson, B (author)
- Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi
-
show less...
-
(creator_code:org_t)
- 1993
- 1993
- English.
-
In: Biomaterials. - 0142-9612 .- 1878-5905. ; 14:3, s. 189-192
- Related links:
-
https://urn.kb.se/re...
Abstract
Subject headings
Close
- After intraocular lens implantation, despite good clinical results, many cataract patients develop a chronic uveitis, caused by an inflammatory response to the implant. One way to improve the biocompatibility of the intraocular lens is to modify the surface by end-point heparin attachment. This study shows that complement activation caused by poly(methyl methacrylate) can be diminished by end-point heparin attachment, as demonstrated by a significant reduction in the generation of C3a and fluid phase terminal complement complexes. It suggests that assessment of complement activation is a good indicator of the biocompatibility of intraocular lenses.
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database