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Suitability Criteri...
Suitability Criteria for Adult Related Donors : A Consensus Statement from the Worldwide Network for Blood and Marrow Transplantation Standing Committee on Donor Issues
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- Worel, Nina (author)
- Med Univ Vienna, Dept Blood Grp Serol & Transfus Med, A-1090 Vienna, Austria.
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- Buser, Andreas (author)
- Swiss Red Cross, Ctr Blood Transfus, Basel, Switzerland.;Univ Basel Hosp, Dept Hematol, CH-4031 Basel, Switzerland.
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- Greinix, Hildegard T. (author)
- Med Univ Graz, Div Hematol, Graz, Austria.
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- Hagglund, Hans (author)
- Karolinska Institutet,Uppsala universitet,Hematologi
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- Navarro, Willis (author)
- Natl Marrow Donor Program, Minneapolis, MN USA.
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- Pulsipher, Michael A. (author)
- Univ Utah, Div Hematol & Hematol Malignancies, Huntsman Canc Inst, Primary Childrens Hosp, Salt Lake City, UT USA.
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- de Faveri, Grazia Nicoloso (author)
- Swiss Blood Stem Cell, Bern, Switzerland.
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- Bengtsson, Mats (author)
- Uppsala universitet,Klinisk immunologi,Swedish Bone Marrow Donors, Tobias Registry, Uppsala, Sweden.
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- Billen, Annelies (author)
- UCL Canc Inst, London, England.
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- Espino, German (author)
- Univ Hosp Caja del Seguro Social, Hematol & Bone Marrow Transplantat Sect, Dept Internal Med, Panama City, Panama.
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- Fechter, Mirjam (author)
- Leiden Univ, Med Ctr, Europdonor Fdn Leiden, Leiden, Netherlands.
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- Giudice, Valeria (author)
- S Orsola Malpighi Univ Hosp, Dept Immunohematol & Transfus Med, Bologna, Italy.
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- Hoelig, Kristina (author)
- Tech Univ Dresden, Univ Hosp Carl Gustav Cams, Dept Internal Med 1, D-01062 Dresden, Germany.
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- Kanamori, Heiwa (author)
- Kanagawa Canc Ctr, Dept Hematol, Yokohama, Kanagawa, Japan.
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- Kodera, Yoshihisa (author)
- Aichi Med Univ, Asia Pacific Blood & Marrow Transplantat Grp, Sch Med, Nagakute, Aichi 48011, Japan.;Aichi Med Univ, Dept Promot Blood & Marrow Transplantat, Sch Med, Nagakute, Aichi 48011, Japan.
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- Leitner, Gerda (author)
- Med Univ Vienna, Dept Blood Grp Serol & Transfus Med, A-1090 Vienna, Austria.
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- Netelenbos, Tanja (author)
- Leiden Univ, Dept Immunohematol & Blood Transfus, Med Ctr, Leiden, Netherlands.
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- Niedervvieser, Dietger (author)
- Univ Hosp Leipzig, Dept Hematol, Leipzig, Germany.
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- van Walraven, Suzanna M. (author)
- Leiden Univ, Med Ctr, Europdonor Fdn Leiden, Leiden, Netherlands.;World Marrow Donor Assoc, Eth Working Grp, Leiden, Netherlands.;Oxford Univ Hosp NHS Trust, British Bone Marrow Donor Registry, Oxford, England.
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- Rocha, Vanderson (author)
- NHS BT, Cord Blood Banks, Oxford, England.
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- Torosian, Tigran (author)
- Fdn DKMS Polska, Warsaw, Poland.
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- Vergueiro, Carmen (author)
- FCM Santa Casa de Selo Paulo, Disciplina Hematol & Oncol, Sao Paulo, Brazil.
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- Weisdorf, Daniel (author)
- Univ Minnesota, Bone Marrow Transplant Program, Minneapolis, MN 55455 USA.
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- Yabe, Hiromasa (author)
- Tokai Univ, Sch Med, Dept Cell Transplantat & Regenerat Med, Tokyo 151, Japan.
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- Halter, Joerg P. (author)
- Univ Basel Hosp, Dept Hematol, CH-4031 Basel, Switzerland.
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Med Univ Vienna, Dept Blood Grp Serol & Transfus Med, A-1090 Vienna, Austria Swiss Red Cross, Ctr Blood Transfus, Basel, Switzerland.;Univ Basel Hosp, Dept Hematol, CH-4031 Basel, Switzerland. (creator_code:org_t)
- Elsevier BV, 2015
- 2015
- English.
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In: Biology of blood and marrow transplantation. - : Elsevier BV. - 1083-8791 .- 1523-6536. ; 21:12, s. 2052-2060
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Abstract
Subject headings
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- The number of allogeneic hematopoietic stem cell (HSC) transplants performed globally each year continues to increase. Advances in HLA typing, better supportive care, and administration of reduced-intensity conditioning regimens allow treatment of older patients with older sibling donors. Pretransplant donor assessment and testing are very important processes affecting the quality and safety of donation. For unrelated HSC donors detailed recommendations for health assessment have been published, allowing donation only if they are unrestrictedly healthy. Eligibility criteria for related donors are less strict and vary significantly between centers. In situations where a family donor does not meet the suitability criteria for unrelated donors, involved physicians often struggle with the decision whether the matched relative is suitable for donation or not. On behalf of the Worldwide Network for Blood and Marrow Transplantation Standing Committee on Donor Issues, we intended to develop a consensus document with recommendations for donor workup and final clearance of family donors who would not be able to serve as unrelated donors because of their age or pre-existing diseases. This article covers different topics intending to support decision-making, with the goal of minimizing medical risk to the donor and protection of the recipient from transmissible diseases.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Keyword
- Related stem cell donor
- Suitability criteria
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Worel, Nina
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Buser, Andreas
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Greinix, Hildega ...
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Hagglund, Hans
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Navarro, Willis
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Pulsipher, Micha ...
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show more...
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de Faveri, Grazi ...
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Bengtsson, Mats
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Billen, Annelies
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Espino, German
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Fechter, Mirjam
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Giudice, Valeria
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Hoelig, Kristina
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Kanamori, Heiwa
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Kodera, Yoshihis ...
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Leitner, Gerda
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Netelenbos, Tanj ...
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Niedervvieser, D ...
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van Walraven, Su ...
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Rocha, Vanderson
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Torosian, Tigran
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Vergueiro, Carme ...
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Weisdorf, Daniel
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Yabe, Hiromasa
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Halter, Joerg P.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Immunology in th ...
- Articles in the publication
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Biology of blood ...
- By the university
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Uppsala University
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Karolinska Institutet