Search: onr:"swepub:oai:DiVA.org:uu-274454" >
Rapid and Efficient...
Rapid and Efficient Conversion of (CO2)-C-11 to (CO)-C-11 through Silacarboxylic Acids : Applications in Pd-Mediated Carbonylations
-
- Nordeman, Patrik (author)
- Uppsala universitet,Institutionen för läkemedelskemi
-
- Friis, Stig D. (author)
- Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, Carbon Dioxide Activat Ctr CADIAC, DK-8000 Aarhus C, Denmark.;Aarhus Univ, Dept Chem, DK-8000 Aarhus C, Denmark.
-
- Andersen, Thomas L. (author)
- Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, Carbon Dioxide Activat Ctr CADIAC, DK-8000 Aarhus C, Denmark.;Aarhus Univ, Dept Chem, DK-8000 Aarhus C, Denmark.
-
show more...
-
- Audrain, Helene (author)
- Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, Carbon Dioxide Activat Ctr CADIAC, DK-8000 Aarhus C, Denmark.;Aarhus Univ, Dept Chem, DK-8000 Aarhus C, Denmark.
-
- Larhed, Mats (author)
- Uppsala universitet,Institutionen för läkemedelskemi
-
- Skrydstrup, Troels (author)
- Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, Carbon Dioxide Activat Ctr CADIAC, DK-8000 Aarhus C, Denmark.;Aarhus Univ, Dept Chem, DK-8000 Aarhus C, Denmark.
-
- Antoni, Gunnar (author)
- Uppsala universitet,Institutionen för läkemedelskemi
-
show less...
-
(creator_code:org_t)
- 2015-10-23
- 2015
- English.
-
In: Chemistry - A European Journal. - : Wiley. - 0947-6539 .- 1521-3765. ; 21:49, s. 17601-17604
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Herein, we present a new rapid, efficient, and low-cost radiosynthetic protocol for the conversion of (CO2)-C-11 to (CO)-C-11 and its subsequent application in Pd-mediated reactions of importance for PET applications. This room-temperature methodology, using readily available chemical reagents, is carried out in simple glass vials, thus eliminating the need for expensive and specialized high-temperature equipment to access (CO)-C-11. With this fast and near-quantitative conversion of (CO2)-C-11 into (CO)-C-11, aryl and heteroaryl iodides were easily converted into a broad selection of biologically active amides in radiochemical yields ranging from 29-84 %.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Läkemedelskemi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medicinal Chemistry (hsv//eng)
Keyword
- carbon monoxide
- carbon-11
- carbon dioxide fixation
- positron emission tomography
- radiochemistry
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database