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Outcome Preferences...
Outcome Preferences in Patients With Noninfectious Uveitis : Results of a Best-Worst Scaling Study
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- Yu, Tsung (author)
- Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.;Univ Zurich, Epidemiol Biostat & Prevent Inst, CH-8006 Zurich, Switzerland.
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- Holbrook, Janet T. (author)
- Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.
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- Thorne, Jennifer E. (author)
- Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.;Johns Hopkins Univ, Sch Med, Dept Ophthalmol, Wilmer Eye Inst, Baltimore, MD 21205 USA.
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- Flynn, Terry N. (author)
- Uppsala universitet,Centrum för forsknings- och bioetik
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- Van Natta, Mark L. (author)
- Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.
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- Puhan, Milo A. (author)
- Univ Zurich, Epidemiol Biostat & Prevent Inst, CH-8006 Zurich, Switzerland.
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Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA;Univ Zurich, Epidemiol Biostat & Prevent Inst, CH-8006 Zurich, Switzerland. Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA. (creator_code:org_t)
- Association for Research in Vision and Ophthalmology (ARVO), 2015
- 2015
- English.
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In: Investigative Ophthalmology and Visual Science. - : Association for Research in Vision and Ophthalmology (ARVO). - 0146-0404 .- 1552-5783. ; 56:11, s. 6864-6872
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- PURPOSE. To estimate patient preferences regarding potential adverse outcomes of local versus systemic corticosteroid therapies for noninfectious uveitis by using a best-worst scaling (BWS) approach. METHODS. Local and systemic therapies are alternatives for noninfectious uveitis that have different potential adverse outcomes. Patients participating in the Multicenter Uveitis Steroid Treatment Trial Follow-up Study (MUST FS) and additional patients with a history of noninfectious uveitis treated at two academic medical centers (Johns Hopkins University and University of Pennsylvania) were surveyed about their preferences regarding six adverse outcomes deemed important to patients. Using "case 1'' BWS, patients were asked to repeatedly select the most and least worrying from a list of outcomes (in the survey three outcomes per task). RESULTS. Eighty-two patients in the MUST FS and 100 patients treated at the academic medical centers completed the survey. According to BWS, patients were more likely to select vision not meeting the requirement for driving (individual BWS score: median = 3, interquartile range, 0-5), development of glaucoma (2, 1-4), and needing eye surgery (1, 0-3) as the most worrying outcomes as compared to needing medicine for high blood pressure/cholesterol (2, 4 to 0), development of cataracts (2, 3 to 1), or infection (sinusitis) (3, 5 to 0). Larger BWS scores indicated the outcomes were more worrying to patients. CONCLUSIONS. Patients with noninfectious uveitis considered impaired vision, development of glaucoma, and need for eye surgery worrying adverse outcomes, which suggests that it is especially desirable to avoid these outcomes if possible. (ClinicalTrials.gov number, NCT00132691.)
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
Keyword
- patient preferences
- uveitis
- medical decision making
Publication and Content Type
- ref (subject category)
- art (subject category)
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