Search: onr:"swepub:oai:DiVA.org:uu-279545" >
Definition of noctu...
Definition of nocturnal gastroesophageal reflux for studies on respiratory diseases
-
- Emilsson, Össur Ingi (author)
- Uppsala universitet,Lung- allergi- och sömnforskning,Univ Iceland, Fac Med, Reykjavik, Iceland.;Landspitali Univ Hosp, Dept Resp Med & Sleep, Reykjavik, Iceland.
-
- Benediktsdottir, Bryndis (author)
- Univ Iceland, Fac Med, Reykjavik, Iceland.;Landspitali Univ Hosp, Dept Resp Med & Sleep, Reykjavik, Iceland.
-
- Olafsson, Isleifur (author)
- Landspitali Univ Hosp, Dept Clin Biochem, Reykjavik, Iceland.
-
show more...
-
- Cook, Elizabeth (author)
- Landspitali Univ Hosp, Dept Clin Biochem, Reykjavik, Iceland.
-
- Juliusson, Sigurdur (author)
- Univ Iceland, Fac Med, Reykjavik, Iceland.;Landspitali Univ Hosp, Dept Ear Nose & Throat, Reykjavik, Iceland.
-
- Berg, Sören (author)
- Lund University,Lunds universitet,Öron-, näs- och halssjukdomar, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Otorhinolaryngology (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Univ, Dept Otolaryngol & Head & Neck Surg, Lund, Sweden.
-
- Nordang, Leif (author)
- Uppsala universitet,Öron-, näs- och halssjukdomar
-
- Björnsson, Einar Stefan (author)
- Univ Iceland, Fac Med, Reykjavik, Iceland.;Landspitali Univ Hosp, Dept Gastroenterol, Reykjavik, Iceland.
-
- Gudlaugsdottir, Sunna (author)
- Landspitali Univ Hosp, Dept Gastroenterol, Reykjavik, Iceland.
-
- Gudmundsdottir, Anna Soffia (author)
- Landspitali Univ Hosp, Dept Gastroenterol, Reykjavik, Iceland.
-
- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
-
- Gislason, Thorarinn (author)
- Univ Iceland, Fac Med, Reykjavik, Iceland.;Landspitali Univ Hosp, Dept Resp Med & Sleep, Reykjavik, Iceland.
-
show less...
-
(creator_code:org_t)
- 2016-01-29
- 2016
- English.
-
In: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 51:5, s. 524-530
- Related links:
-
http://www.ncbi.nlm....
-
show more...
-
http://dx.doi.org/10...
-
https://urn.kb.se/re...
-
https://doi.org/10.3...
-
https://lup.lub.lu.s...
-
show less...
Abstract
Subject headings
Close
- Objective Nocturnal gastroesophageal reflux (nGER) has been associated with respiratory diseases. Our aim was to study a questionnaire method to identify nGER subjects with respiratory involvement in a general population. Material and methods A subgroup of Icelandic participants in the European Community Respiratory Health Survey III (ECRHS III) reporting symptoms of nGER (n =48) as well as age and gender paired controls (n =42) were studied further by a structured interview, questionnaires, laryngeal fibrescopy, and exhaled breath condensate. A subgroup underwent 24-h oesophageal pH impedance (24-h MII-pH) measurements. Symptoms of nGER were assessed with a modified version of the reflux disease questionnaire (RDQ), where symptoms were divided into daytime and nocturnal. A report of nGER both at baseline and at follow-up was defined as persistent nGER. Results Participants reporting persistent nGER had significantly more signs of laryngopharyngeal reflux according to the reflux finding score than those without nGER (Mean +/- SD: 5.1 +/- 2.3 vs. 3.9 +/- 2.2, p =0.02). Of the 16 persistent nGER subjects that underwent 24-h MII-pH, 11 had abnormal gastroesophageal reflux, but none of three control subjects (69% vs. 0%). Pepsin was more commonly found in exhaled breath condensate in the nGER group (67% vs. 45%, p =0.04). Conclusions Participants with nGER symptoms at least once a month, reported on two occasions, had a high level of positive 24-h MII-pH measurements, laryngeal inflammation and pepsin in exhaled breath condensate. This nGER definition identified a representable group for studies on nGER and respiratory diseases in a general population.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Keyword
- Asthma
- laryngopharyngeal reflux
- nocturnal gastroesophageal reflux
- pepsin
- reflux disease questionnaire
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Emilsson, Össur ...
-
Benediktsdottir, ...
-
Olafsson, Isleif ...
-
Cook, Elizabeth
-
Juliusson, Sigur ...
-
Berg, Sören
-
show more...
-
Nordang, Leif
-
Björnsson, Einar ...
-
Gudlaugsdottir, ...
-
Gudmundsdottir, ...
-
Janson, Christer
-
Gislason, Thorar ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Gastroenterology ...
- Articles in the publication
-
Scandinavian Jou ...
- By the university
-
Uppsala University
-
Lund University