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Capacitating epista...
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Pettersson, MatsSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences
(author)
Capacitating epistasis--detection and role in the genetic architecture of complex traits.
- Article/chapterEnglish2015
Publisher, publication year, extent ...
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2014-11-03
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New York, NY :Springer New York,2015
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-294200
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ISBN:9781493921546
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ISBN:9781493921553
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-294200URI
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https://doi.org/10.1007/978-1-4939-2155-3_10DOI
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https://res.slu.se/id/publ/83558URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Here, we discuss the potential role of capacitating epistasis in the genetic architecture of complex traits. Two alternative methods for identifying such gene-gene interactions in genetic association studies-mapping of variance controlling loci and the variance plane ratio (VPR) method-are introduced. An overview of the theoretical foundation of the methods is presented together with a discussion on their implementation and available software for performing these analyses. We conclude by highlighting a few examples of capacitating epistasis described in the literature and its potential impacts on the genetics of complex traits.
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Carlborg, ÖrjanSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences(Swepub:slu)48083
(author)
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Sveriges lantbruksuniversitetInstitutionen för kliniska vetenskaper (KV)
(creator_code:org_t)
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Sveriges lantbruksuniversitet
Related titles
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In:Methods in Molecular BiologyNew York, NY : Springer New York1253:1253, s. 185-1961064-37451940-6029
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In:Epistasis : methods and protocolsNew York, NY : Springer New York1253:1253, s. 185-1969781493921546
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