Search: onr:"swepub:oai:DiVA.org:uu-299052" >
Work Loss Duration ...
-
Chen, LingjingKarolinska Institutet
(author)
Work Loss Duration and Predictors Following Rectal Cancer Treatment among Patients with and without Prediagnostic Work Loss
- Article/chapterEnglish2016
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-299052
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-299052URI
-
https://doi.org/10.1158/1055-9965.EPI-16-0112DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:133703597URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Background: The number of working-age rectal cancer survivors is increasing due to early detection and improved treatment. However, work loss duration and predictors among them have not been studied thoroughly. Methods: We identified 3,438 patients with stage I-III rectal cancer, 18 to 61 years of age in the Swedish Colorectal Cancer Register 1996-2009. Information on work loss due to sick leave or disability pension was collected from 2 years before diagnosis to 5 years after (until December 31st, 2013). Incidence rate ratios (IRR) of work loss were estimated in a negative binominal model by clinical characteristics for the 1st and 2nd-5th years after diagnosis. Patients were stratified by prediagnostic work loss. Results: Patients without prediagnostic work loss (74%) experienced median 147 days (25th and 75th percentile: 55 and 281) of work loss during the 1st year after diagnosis. Work loss rates (2nd-5th years) were significantly increased among relapse-free patients diagnosed in stage III [IRR = 1.92; 95% confidence interval (CI), 1.52-2.43], operated with abdominoperineal resection (IRR = 1.26; 95% CI, 1.03-1.56), and treated with neoadjuvant (chemo) radiotherapy (IRR = 1.46; 95% CI, 1.06-2.02). Patients with prediagnostic work loss (26%) experienced median 336 days (25th and 75th percentile: 183 and 365) of work loss during the 1st year, and rates did not vary clinically till 5 years. Conclusion: Without prediagnostic work loss, disease-and treatment-related factors could help identify rectal cancer patients in need of early interventions to facilitate return to work. Impact: Clinical awareness around prediagnostic and postdiagnostic work loss and individualized cancer rehabilitation programs should be emphasized among cancer survivors.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Glimelius, IngridKarolinska Institutet,Uppsala universitet,Experimentell och klinisk onkologi,Karolinska Inst, Dept Med Solna, Clin Epidemiol Unit, Stockholm, Sweden.(Swepub:uu)inggl846
(author)
-
Neovius, MartinKarolinska Institutet
(author)
-
Ekberg, SaraKarolinska Institutet
(author)
-
Martling, AnnaKarolinska Institutet
(author)
-
Eloranta, SandraKarolinska Institutet
(author)
-
Smedby, Karin E.Karolinska Institutet
(author)
-
Karolinska InstitutetExperimentell och klinisk onkologi
(creator_code:org_t)
Related titles
-
In:Cancer Epidemiology, Biomarkers and Prevention25:6, s. 987-9941055-99651538-7755
Internet link
Find in a library
To the university's database