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Risk factors for su...
Risk factors for suicide among patients with schizophrenia : a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid
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- Neider, Daniel (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset
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- Lindström, Leif H. (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset
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- Boden, Robert (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset
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(creator_code:org_t)
- 2016
- 2016
- English.
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In: Neuropsychiatric Disease and Treatment. - 1176-6328 .- 1178-2021. ; 12, s. 1711-1714
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Abstract
Subject headings
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- Background: The objective of this study was to investigate the association between 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF), bullying, and later suicide among patients with schizophrenia. Methods: Ninety-nine patients with schizophrenia were included. Correlations of clinical factors, 5-HIAA and HVA, and later suicide were investigated. Results: Twelve patients committed suicide (12%) during a 28-year follow-up period. Later suicide was correlated to bullying in childhood (P=0.02) and a lower quotient of HVA/5-HIAA in CSF (P<0.05). Conclusion: Suicide in schizophrenia is related to childhood exposedness and CSF neurotransmitter levels.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- psychosis
- risk factors
- bullying
- HVA
- 5-HIAA
- CSF
Publication and Content Type
- ref (subject category)
- art (subject category)
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