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Risk factors for su...
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Neider, DanielUppsala universitet,Psykiatri, Akademiska sjukhuset
(author)
Risk factors for suicide among patients with schizophrenia : a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid
- Article/chapterEnglish2016
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2016
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electronicrdacarrier
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LIBRIS-ID:oai:DiVA.org:uu-300101
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300101URI
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https://doi.org/10.2147/NDT.S107178DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background: The objective of this study was to investigate the association between 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF), bullying, and later suicide among patients with schizophrenia. Methods: Ninety-nine patients with schizophrenia were included. Correlations of clinical factors, 5-HIAA and HVA, and later suicide were investigated. Results: Twelve patients committed suicide (12%) during a 28-year follow-up period. Later suicide was correlated to bullying in childhood (P=0.02) and a lower quotient of HVA/5-HIAA in CSF (P<0.05). Conclusion: Suicide in schizophrenia is related to childhood exposedness and CSF neurotransmitter levels.
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Lindström, Leif H.Uppsala universitet,Psykiatri, Akademiska sjukhuset(Swepub:uu)leiflind
(author)
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Boden, RobertUppsala universitet,Psykiatri, Akademiska sjukhuset(Swepub:uu)robod677
(author)
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Uppsala universitetPsykiatri, Akademiska sjukhuset
(creator_code:org_t)
Related titles
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In:Neuropsychiatric Disease and Treatment12, s. 1711-17141176-63281178-2021
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