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Gender-related diff...
Gender-related differences in urothelial carcinoma of the bladder : a population-based study from the Swedish National Registry of Urinary Bladder Cancer
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- Thorstenson, Andreas (author)
- Karolinska Institute,Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institute, Stockholm, Sweden; Department of Surgery, Section of Urology, Capio St Göran’s Hospital, Stockholm, Sweden
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- Hagberg, Oskar (author)
- Lund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Regional Cancer Center, Lund University, Lund, Sweden;
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- Ljungberg, Börje (author)
- Umeå University,Umeå universitet,Urologi och andrologi,Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden
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- Liedberg, Fredrik (author)
- Lund University,Lunds universitet,Urologi,Forskargrupper vid Lunds universitet,Urology,Lund University Research Groups,Skåne University Hospital,Department of Urology, SUS, Lund University, Malmö, Sweden
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- Jancke, Georg (author)
- Linköpings universitet,Linköping University,Avdelningen för kliniska vetenskaper,Medicinska fakulteten,Region Östergötland, Urologiska kliniken i Östergötland
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- Holmang, Sten (author)
- Sahlgrens Univ Hosp, Dept Urol, Gothenburg, Sweden.,Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden
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- Malmström, Per-Uno (author)
- Uppsala universitet,Urologkirurgi,Department of Urology, Uppsala University Hospital, Uppsala, Sweden
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- Hosseini, Abolfazl (author)
- Karolinska Institute,Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institute, Stockholm, Sweden
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- Jahnson, Staffan (author)
- Linköpings universitet,Linköping University,Avdelningen för kliniska vetenskaper,Medicinska fakulteten,Region Östergötland, Urologiska kliniken i Östergötland
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(creator_code:org_t)
- 2016-03-22
- 2016
- English.
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In: Scandinavian journal of urology. - : Informa UK Limited. - 2168-1805 .- 2168-1813. ; 50:4, s. 292-297
- Related links:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Subject headings
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- Objective: The aim of this investigation was to describe tumour characteristics, treatments and survival in patients with urinary bladder cancer (UBC) in a national population-based cohort, with special reference to gender-related differences. Material and methods: All primary UBC patients with urothelial pathology reported to the Swedish National Registry of Urinary Bladder Cancer (SNRUBC) from 1997 to 2011 were included in the study. Groups were compared regarding tumour, node, metastasis classification, primary treatment and survival. Results: In total, 30,310 patients (74.9% male, 25.1% female) with UBC were analysed. A larger proportion of women than men had stage T2-T4 (p<0.001), and women also had more G1 tumours (p<0.001). However, compared to women, a larger proportion of men with carcinoma in situ or T1G3 received intravesical treatment with bacillus Calmette-Guerin or intravesical chemotherapy, and a larger proportion of men with stage T2-T4 underwent radical cystectomy (38% men vs 33% women, p<0.0001). The cancer-specific survival at 5 years was 77% for men and 72% for women (p<0.001), and the relative survival at 5 years was 72% for men and 69% for women (p<0.001). Conclusions: In this population-based cohort comprising virtually all patients diagnosed with UBC in Sweden between 1997 and 2011, female gender was associated with inferior cancer-specific and relative survival. Although women had a higher rate of aggressive tumours, a smaller proportion of women than men received optimal treatment.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- Bladder cancer
- female
- gender
- male
- population-based
- survival
Publication and Content Type
- ref (subject category)
- art (subject category)
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