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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04721naa a2200457 4500 | |
| 001 | oai:DiVA.org:uu-305771 | |
| 003 | SwePub | |
| 008 | 161021s2016 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:134399241 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3057712 URI |
| 024 | 7 | a https://doi.org/10.1007/s00330-016-4273-y2 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1343992412 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Loizou, L.u Karolinska Institutet4 aut |
| 245 | 1 0 | a Multidetector CT of pancreatic ductal adenocarcinoma :b Effect of tube voltage and iodine load on tumour conspicuity and image quality |
| 264 | c 2016-03-10 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2016 |
| 338 | a print2 rdacarrier | |
| 520 | a OBJECTIVES: To compare a low-tube-voltage with or without high-iodine-load multidetector CT (MDCT) protocol with a normal-tube-voltage, normal-iodine-load (standard) protocol in patients with pancreatic ductal adenocarcinoma (PDAC) with respect to tumour conspicuity and image quality.METHODS: Thirty consecutive patients (mean age: 66 years, men/women: 14/16) preoperatively underwent triple-phase 64-channel MDCT examinations twice according to: (i) 120-kV standard protocol (PS; 0.75 g iodine (I)/kg body weight, n = 30) and (ii) 80-kV protocol A (PA; 0.75 g I/kg, n = 14) or protocol B (PB; 1 g I/kg, n = 16). Two independent readers evaluated tumour delineation and image quality blindly for all protocols. A third reader estimated the pancreas-to-tumour contrast-to-noise ratio (CNR). Statistical analysis was performed with the Chi-square test.RESULTS: Tumour delineation was significantly better in PB and PA compared with PS (P = 0.02). The evaluation of image quality was similar for the three protocols (all, P > 0.05). The highest CNR was observed with PB and was significantly better compared to PA (P = 0.02) and PS (P = 0.0002).CONCLUSION: In patients with PDAC, a low-tube-voltage, high-iodine-load protocol improves tumour delineation and CNR leading to higher tumour conspicuity compared to standard protocol MDCT.KEY POINTS: • Low-tube-voltage high-iodine-load MDCT improves pancreatic cancer conspicuity compared to a standard protocol. • The pancreas-to-tumour attenuation difference increases significantly by reducing the tube voltage. • The radiation exposure dose decreases by reducing the tube voltage. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng |
| 653 | a Pancreatic neoplasm; Image enhancement; Contrast media; Multidetector computed tomography; Radiation dosage | |
| 700 | 1 | a Albiin, N.u Karolinska Institutet4 aut |
| 700 | 1 | a Leidner, B.u Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden4 aut |
| 700 | 1 | a Axelsson, E.u Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden4 aut |
| 700 | 1 | a Fischer, M. A.u Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden4 aut |
| 700 | 1 | a Grigoriadis, A.u Karolinska Institutet4 aut |
| 700 | 1 | a Del Chiaro, M.u Karolinska Institutet4 aut |
| 700 | 1 | a Segersvärd, R.u Karolinska Institutet4 aut |
| 700 | 1 | a Verbeke, C.u Karolinska Institutet4 aut |
| 700 | 1 | a Sundin, Andersu Uppsala universitet,Radiologi,Univ Uppsala Hosp, Dept Radiol, S-75185 Uppsala, Sweden4 aut0 (Swepub:uu)anderssu |
| 700 | 1 | a Kartalis, N.u Karolinska Institutet4 aut |
| 710 | 2 | a Karolinska Institutetb Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Div Med Imaging & Technol, S-14186 Stockholm, Sweden; C1 46 Karolinska Univ Hosp Huddinge, Dept Radiol, S-14186 Stockholm, Sweden4 org |
| 773 | 0 | t European Radiologyd : Springer Science and Business Media LLCg 26:11, s. 4021-4029q 26:11<4021-4029x 0938-7994x 1432-1084 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-305771 |
| 856 | 4 8 | u https://doi.org/10.1007/s00330-016-4273-y |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:134399241 |
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