Search: onr:"swepub:oai:DiVA.org:uu-307245" >
Comparison of Flow ...
-
Matuszewski, Damian J.Uppsala universitet,Bildanalys och människa-datorinteraktion,Science for Life Laboratory, SciLifeLab
(author)
Comparison of Flow Cytometry and Image-Based Screening for Cell Cycle Analysis
- Article/chapterEnglish2016
Publisher, publication year, extent ...
-
2016-07-01
-
Cham :Springer,2016
-
electronicrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-307245
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307245URI
-
https://doi.org/10.1007/978-3-319-41501-7_70DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:kon swepub-publicationtype
Notes
-
Quantitative cell state measurements can provide a wealth of information about mechanism of action of chemical compounds and gene functionality. Here we present a comparison of cell cycle disruption measurements from commonly used flow cytometry (generating onedimensional signal data) and bioimaging (producing two-dimensional image data). Our results show high correlation between the two approaches indicating that image-based screening can be used as an alternative to flow cytometry. Furthermore, we discuss the benefits of image informatics over conventional single-signal flow cytometry.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Sintorn, Ida-MariaUppsala universitet,Bildanalys och människa-datorinteraktion,Science for Life Laboratory, SciLifeLab(Swepub:uu)idsin102
(author)
-
Puigvert, Jordi CarrerasUppsala universitet,Science for Life Laboratory, SciLifeLab,Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
(author)
-
Wählby, CarolinaUppsala universitet,Bildanalys och människa-datorinteraktion,Science for Life Laboratory, SciLifeLab(Swepub:uu)cli05194
(author)
-
Uppsala universitetBildanalys och människa-datorinteraktion
(creator_code:org_t)
Related titles
-
In:Image Analysis And Recognition (ICIAR 2016)Cham : Springer, s. 623-630
Internet link
To the university's database