Search: onr:"swepub:oai:DiVA.org:uu-310569" >
Surgical Replacemen...
-
Fytagoridis, AndersKarolinska Institutet,Umeå universitet,Klinisk neurovetenskap,Neurosurgery, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm. Asia-Pacific Centre for Neuromodulation, Queensland Brain Institute, University of Queensland,Karolinska Inst, Dept Clin Neurosci, Neurosurg, Stockholm, Sweden.;Umeå Univ, Dept Pharmacol & Clin Neurosci, Unit Funct & Stereotact Neurosurg, Umeå, Sweden.;Univ Queensland, Queensland Brain Inst, Asia Pacific Ctr Neuromodulat, Brisbane, Qld 4072, Australia.,Karolinska Institute, Sweden; Umeå University, Sweden; University of Queensland, Australia
(author)
Surgical Replacement of Implantable Pulse Generator in Deep Brain Stimulation : Adverse Events and Risk Factors in a Multicenter Cohort
- Article/chapterEnglish2016
Publisher, publication year, extent ...
-
2016-08-24
-
S. Karger AG,2016
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-310569
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-310569URI
-
https://doi.org/10.1159/000447521DOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128489URI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-133022URI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:134567267URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Funding Agencies|Umea University; Foundation for Clinical Neuroscience at the University Hospital of Umea; Foundation for Clinical Research of the Stockholm County Council
-
Background: Deep brain stimulation (DBS) is a growing treatment modality, and most DBS systems require replacement of the implantable pulse generator (IPG) every few years. The literature regarding the potential impact of adverse events of IPG replacement on the longevity of DBS treatments is rather scarce. Objective: To investigate the incidence of adverse events, including postoperative infections, associated with IPG replacements in a multicenter cohort. Methods: The medical records of 808 patients from one Australian and five Swedish DBS centers with a total of 1,293 IPG replacements were audited. A logistic regression model was used to ascertain the influence of possible predictors on the incidence of adverse events. Results: The overall incidence of major infections was 2.3% per procedure, 3.7% per patient and 1.7% per replaced IPG. For 28 of 30 patients this resulted in partial or complete DBS system removal. There was an increased risk of infection for males (OR 3.6, p = 0.026), and the risk of infection increased with the number of prior IPG replacements (OR 1.6, p < 0.005). Conclusions: The risk of postoperative infection with DBS IPG replacement increases with the number of previous procedures. There is a need to reduce the frequency of IPG replacements.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Heard, TomasUniv Queensland, Queensland Brain Inst, Asia Pacific Ctr Neuromodulat, Brisbane, Qld 4072, Australia.,University of Queensland, Australia
(author)
-
Samuelsson, JenniferUmeå universitet,Klinisk neurovetenskap,Department of Neurosurgery, Sahlgrenska University Hospital, Göteborg,Umeå Univ, Dept Pharmacol & Clin Neurosci, Unit Funct & Stereotact Neurosurg, Umeå, Sweden.;Sahlgrens Univ Hosp, Dept Neurosurg, Gothenburg, Sweden.,Umeå University, Sweden; Sahlgrens University Hospital, Sweden(Swepub:umu)jesa0096
(author)
-
Zsigmond, PeterLinköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Region Östergötland, Neurokirurgiska kliniken US(Swepub:liu)petzs86
(author)
-
Jiltsova, ElenaUppsala universitet,Neurokirurgi,University of Uppsala Hospital, Sweden
(author)
-
Skyrman, SimonKarolinska Institutet
(author)
-
Skoglund, ThomasSahlgrens Univ Hosp, Dept Neurosurg, Gothenburg, Sweden.,Sahlgrens University Hospital, Sweden
(author)
-
Coyne, TerryUniv Queensland, Queensland Brain Inst, Asia Pacific Ctr Neuromodulat, Brisbane, Qld 4072, Australia.;Brizbrain & Spine, Brisbane, Qld, Australia.,University of Queensland, Australia; Brizbrain and Spine, Australia
(author)
-
Silburn, PeterUniv Queensland, Queensland Brain Inst, Asia Pacific Ctr Neuromodulat, Brisbane, Qld 4072, Australia.,University of Queensland, Australia
(author)
-
Blomstedt, PatricUmeå universitet,Klinisk neurovetenskap,Umeå Univ, Dept Pharmacol & Clin Neurosci, Unit Funct & Stereotact Neurosurg, Umeå, Sweden.,Umeå University, Sweden(Swepub:umu)pabl0002
(author)
-
Umeå universitetKlinisk neurovetenskap
(creator_code:org_t)
Related titles
-
In:Stereotactic and Functional Neurosurgery: S. Karger AG94:4, s. 235-2391011-61251423-0372
Internet link
Find in a library
To the university's database
- By the author/editor
-
Fytagoridis, And ...
-
Heard, Tomas
-
Samuelsson, Jenn ...
-
Zsigmond, Peter
-
Jiltsova, Elena
-
Skyrman, Simon
-
show more...
-
Skoglund, Thomas
-
Coyne, Terry
-
Silburn, Peter
-
Blomstedt, Patri ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Neurology
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Surgery
- Articles in the publication
-
Stereotactic and ...
- By the university
-
Uppsala University
-
Umeå University
-
Linköping University
-
Karolinska Institutet