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  • Barazzoni, RDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (author)

Carbohydrates and insulin resistance in clinical nutrition : Recommendations from the ESPEN expert group.

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • Elsevier BV,2017
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-317128
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-317128URI
  • https://doi.org/10.1016/j.clnu.2016.09.010DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-57777URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:135704730URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Growing evidence underscores the important role of glycemic control in health and recovery from illness. Carbohydrate ingestion in the diet or administration in nutritional support is mandatory, but carbohydrate intake can adversely affect major body organs and tissues if resulting plasma glucose becomes too high, too low, or highly variable. Plasma glucose control is especially important for patients with conditions such as diabetes or metabolic stress resulting from critical illness or surgery. These patients are particularly in need of glycemic management to help lessen glycemic variability and its negative health consequences when nutritional support is administered. Here we report on recent findings and emerging trends in the field based on an ESPEN workshop held in Venice, Italy, 8-9 November 2015. Evidence was discussed on pathophysiology, clinical impact, and nutritional recommendations for carbohydrate utilization and management in nutritional support. The main conclusions were: a) excess glucose and fructose availability may exacerbate metabolic complications in skeletal muscle, adipose tissue, and liver and can result in negative clinical impact; b) low-glycemic index and high-fiber diets, including specialty products for nutritional support, may provide metabolic and clinical benefits in individuals with obesity, insulin resistance, and diabetes; c) in acute conditions such as surgery and critical illness, insulin resistance and elevated circulating glucose levels have a negative impact on patient outcomes and should be prevented through nutritional and/or pharmacological intervention. In such acute settings, efforts should be implemented towards defining optimal plasma glucose targets, avoiding excessive plasma glucose variability, and optimizing glucose control relative to nutritional support.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Deutz, N E PCenter for Translational Research in Aging & Longevity, Department of Health and Kinesiology, Texas A & M University, College Station TX, USA (author)
  • Biolo, GDepartment of Medical, Surgical and Health Sciences, Internal Medicine, University of Trieste, Trieste, Italy (author)
  • Bischoff, SDepartment of Nutritional Medicine/Prevention, University of Hohenheim, Stuttgart, Germany (author)
  • Boirie, YDepartment of Clinical Nutrition, CHU de Clermont-Ferrand, CRNH, Université d'Auvergne, Clermont-Ferrand, France (author)
  • Cederholm, TKarolinska Institutet,Uppsala universitet,Klinisk nutrition och metabolism,Geriatrik,Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden; Department of Geriatric Medicine, Uppsala University Hospital, Uppsala, Sweden(Swepub:uu)tomce419 (author)
  • Cuerda, CNutrition Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain,Nutrition Unit, Geneva University Hospital, Geneva, Switzerland,Department of Intensive Care, Erasme University Hospital, Brussels, Belgium,Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; University of Southampton, Southampton, United Kingdom (author)
  • Delzenne, NDepartment, Université Catholique de Louvain, Brussels, Belgium (author)
  • Leon Sanz, MDepartment of Medicine, Complutense University, Madrid, Spain,Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy (author)
  • Ljungqvist, Olle,1954-Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Surgery(Swepub:oru)olt (author)
  • Muscaritoli, M (author)
  • Pichard, C (author)
  • Preiser, J C (author)
  • Sbraccia, P (author)
  • Singer, PDepartment of Intensive Care, Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Sackler School of Medicine, Tel Aviv University, Israel (author)
  • Tappy, LDepartment of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (author)
  • Thorens, BCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland (author)
  • Van Gossum, AGastroenterology Service, Hospital Erasme, Brussels, Belgium (author)
  • Vettor, RInternal Medicine Unit and Center for the Study and Integrated Treatment of Obesity, Department of Medicine, Padua University, Padua, Italy (author)
  • Calder, P C (author)
  • Sbraccia, R.Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy (author)
  • Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, ItalyCenter for Translational Research in Aging & Longevity, Department of Health and Kinesiology, Texas A & M University, College Station TX, USA (creator_code:org_t)

Related titles

  • In:Clinical Nutrition: Elsevier BV36:2, s. 355-3630261-56141532-1983

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