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High pressure inert...
High pressure inertial focusing for separating and concentrating bacteria at high throughput
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- Cruz, Javier, 1990- (author)
- Uppsala universitet,Mikrosystemteknik
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- Zadeh, S. Hooshmand (author)
- Uppsala universitet,Institutionen för teknikvetenskaper
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- Graells, Tiscar (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Institutionen för teknikvetenskaper,Univ Autonoma Barcelona, Dept Genet & Microbiol, Barcelona, Spain.
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- Andersson, Martin (author)
- Uppsala universitet,Mikrosystemteknik
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- Malmström, Jonas (author)
- Uppsala universitet,Institutionen för teknikvetenskaper
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- Wu, Zhigang G., 1977- (author)
- Uppsala universitet,Mikrosystemteknik,Huazhong Univ Sci & Technol, State Key Lab Digital Mfg Equipment & Technol, Wuhan, Peoples R China.
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- Hjort, Klas, 1964- (author)
- Uppsala universitet,Mikrosystemteknik
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(creator_code:org_t)
- 2017-06-27
- 2017
- English.
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In: Journal of Micromechanics and Microengineering. - : IOP PUBLISHING LTD. - 0960-1317 .- 1361-6439. ; 27:8
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Abstract
Subject headings
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- Inertial focusing is a promising microfluidic technology for concentration and separation of particles by size. However, there is a strong correlation of increased pressure with decreased particle size. Theory and experimental results for larger particles were used to scale down the phenomenon and find the conditions that focus 1 mu m particles. High pressure experiments in robust glass chips were used to demonstrate the alignment. We show how the technique works for 1 mu m spherical polystyrene particles and for Escherichia coli, not being harmful for the bacteria at 50 mu l min(-1). The potential to focus bacteria, simplicity of use and high throughput make this technology interesting for healthcare applications, where concentration and purification of a sample may be required as an initial step.
Subject headings
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Materialteknik -- Annan materialteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Materials Engineering -- Other Materials Engineering (hsv//eng)
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Keyword
- bacteria separation
- particle separation
- inertial focusing
- high pressure
- glass chips
- PDMS
- microfluidic channel
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Cruz, Javier, 19 ...
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Zadeh, S. Hooshm ...
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Graells, Tiscar
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Andersson, Marti ...
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Malmström, Jonas
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Wu, Zhigang G., ...
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show more...
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Hjort, Klas, 196 ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Physical Science ...
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and Condensed Matter ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Materials Engine ...
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and Other Materials ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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and Analytical Chemi ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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and Physical Chemist ...
- Articles in the publication
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Journal of Micro ...
- By the university
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Uppsala University