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A combined experimental and numerical method to estimate the elastic modulus of single trabeculae

Wu, Dan, 1990- (author)
Uppsala universitet,Tillämpad materialvetenskap,BioMaterial Systems
Joffre, Thomas, 1987- (author)
Uppsala universitet,Tillämpad materialvetenskap,Tillämpad mekanik
Öhman, Caroline (author)
Uppsala universitet,Tillämpad materialvetenskap,Materials in Medicine
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Ferguson, Stephen (author)
Swiss Fed Inst Technol, Inst Biomech, Zurich, Switzerland.
Persson, Cecilia (author)
Uppsala universitet,Tillämpad materialvetenskap,BioMaterial Systems
Isaksson, Per (author)
Uppsala universitet,Tillämpad mekanik
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 (creator_code:org_t)
Elsevier, 2022
2022
English.
In: Journal of The Mechanical Behavior of Biomedical Materials. - : Elsevier. - 1751-6161 .- 1878-0180. ; 125
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The elastic modulus at the single trabecular level is an important parameter for the understanding of the mechanical behavior of trabecular bone. Current methods are commonly limited by the irregular trabecular shape and the accuracy of displacement measurement. The aim of this study was to propose a method to estimate the trabecular modulus overcoming some of these limitations. For high-precision displacement measurements, insitu compression within a synchrotron radiation based X-ray tomograph was used. Trabecular displacements were subsequently estimated by a global digital volume correlation algorithm, followed by high-resolution finite element analyses to account for the irregular geometry. The trabecular elastic moduli were then estimated by comparing the loads from the finite element analyses with those of the experiments. With this strategy, the average elastic modulus was estimated to 3.83 +/- 0.54 GPa for three human trabeculae samples. Though limited by the sample size, the demonstrated method shows a potential to estimate the mechanical properties at the single trabecular level.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Maskinteknik -- Teknisk mekanik (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Mechanical Engineering -- Applied Mechanics (hsv//eng)
NATURVETENSKAP  -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
NATURAL SCIENCES  -- Physical Sciences -- Condensed Matter Physics (hsv//eng)

Keyword

Engineering Science with specialization in Materials Science
Teknisk fysik med inriktning mot materialvetenskap

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