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Self-Reported Healt...
Self-Reported Health and Outcomes in Patients With Stable Coronary Heart Disease
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- Stewart, Ralph A H (author)
- Auckland City Hosp, Auckland, New Zealand
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- Hagström, Emil (author)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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- Held, Claes, 1956- (author)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi,kardiologi
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- Wang, Tom Kai Ming (author)
- Auckland City Hosp, Auckland, New Zealand
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- Armstrong, Paul W (author)
- Univ Alberta, Canadian VIGOUR Ctr, Edmonton, AB, Canada
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- Aylward, Philip E (author)
- Flinders Univ & Med Ctr, South Australian Hlth & Med Res Inst, Adelaide, SA, Australia
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- Cannon, Christopher P (author)
- Brigham & Womens Hosp, Div Cardiovasc, 75 Francis St, Boston, MA 02115 USA.
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- Koenig, Wolfgang (author)
- Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany.;Univ Ulm, Med Ctr, Dept Internal Med Cardiol 2, Ulm, Germany.
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- López-Sendón, José Luis (author)
- Hosp Univ La Paz IdiPaz, Madrid, Spain.
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- Mohler, Emile R, 3rd (author)
- Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.
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- Hadziosmanovic, Nermin (author)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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- Krug-Gourley, Susan (author)
- GlaxoSmithKline, Metab Pathways & Cardiovasc Therapeut Area, King Of Prussia, PA USA.
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- Ramos Corrales, Marco Antonio (author)
- San Jose Satelite Hosp, Naucalpan De Juarez, Mexico.
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- Siddique, Saulat (author)
- Punjab Med Ctr, Jail Rd, Lahore, Punjab, Pakistan.
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- Steg, Philippe Gabriel (author)
- Hop Bichat Claude Bernard, AP HP, Dept Hosp Univ FIRE, Paris, France.;Diderot Univ, Sorbonne Paris Cite, Paris, France.;Royal Brompton Hosp, ICMS, NHLI Imperial Coll, London, England.;FACT, INSERM, U1148, Paris, France.
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- White, Harvey D (author)
- Auckland City Hosp, Auckland, New Zealand.
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- Wallentin, Lars, 1943- (author)
- Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),UCR
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(creator_code:org_t)
- 2017
- 2017
- English.
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In: Journal of the American Heart Association. - 2047-9980. ; 6:8
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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Abstract
Subject headings
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- Background-—The major determinants and prognostic importance of self-reported health in patients with stable coronary heartdisease are uncertain.Methods and Results-—The STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) trialrandomized 15 828 patients with stable coronary heart disease to treatment with darapladib or placebo. At baseline, 98% ofparticipants completed a questionnaire that included the question, “Overall, how do you feel your general health is now?”Possible responses were excellent, very good, good, average, and poor. Adjudicated major adverse cardiac events, whichincluded cardiovascular death, myocardial infarction, and stroke, were evaluated by Cox regression during 3.7 years of follow-upfor participants who reported excellent or very good health (n=2304), good health (n=6863), and average or poor health(n=6361), before and after adjusting for 38 covariates. Self-reported health was most strongly associated with geographicregion, depressive symptoms, and low physical activity (P<0.0001 for all). Poor/average compared with very good/excellentself-reported health was independently associated with major adverse cardiac events (hazard ratio [HR]: 2.30 [95% confidenceinterval (CI), 1.92–2.76]; adjusted HR: 1.83 [95% CI, 1.51–2.22]), cardiovascular mortality (HR: 4.36 [95% CI, 3.09–6.16];adjusted HR: 2.15 [95% CI, 1.45–3.19]), and myocardial infarction (HR: 1.87 [95% CI, 1.46–2.39]; adjusted HR: 1.68 [95% CI,1.25–2.27]; P<0.0002 for all).Conclusions-—Self-reported health is strongly associated with geographical region, mood, and physical activity. In a globalcoronary heart disease population, self-reported health was independently associated with major cardiovascular events andmortality beyond what is measurable by established risk indicators.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- coronary artery disease
- general health
- prognostic studies
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Stewart, Ralph A ...
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Hagström, Emil
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Held, Claes, 195 ...
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Wang, Tom Kai Mi ...
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Armstrong, Paul ...
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Aylward, Philip ...
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Cannon, Christop ...
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Koenig, Wolfgang
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López-Sendón, Jo ...
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Mohler, Emile R, ...
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Hadziosmanovic, ...
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Krug-Gourley, Su ...
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Ramos Corrales, ...
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Siddique, Saulat
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Steg, Philippe G ...
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White, Harvey D
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Wallentin, Lars, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Journal of the A ...
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Uppsala University