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Antiplatelet Agents for the Treatment and Prevention of Coronary Atherothrombosis

Patrono, Carlo (author)
Catholic Univ, Sch Med, Dept Pharmacol, Largo F Vito 1, I-00168 Rome, Italy.
Morais, Joao (author)
Santo Andres Hosp, Div Cardiol, Leiria, Portugal.
Baigent, Colin (author)
Univ Oxford, Nuffield Dept Populat Hlth, MRC Populat Hlth Res Unit, Oxford, England.
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Collet, Jean-Philippe (author)
Sorbonne Univ Paris 6, Hop Pitie Salpetriere, APHP, ACT Study Grp,Inst Cardiol,INSERM,UMRS 1166, Paris, France.
Fitzgerald, Desmond (author)
Univ Limerick, Limerick, Ireland.
Halvorsen, Sigrun (author)
Oslo Univ Hosp Ulleval, Dept Cardiol, Oslo, Norway.;Univ Oslo, Oslo, Norway.
Rocca, Bianca (author)
Catholic Univ, Sch Med, Dept Pharmacol, Largo F Vito 1, I-00168 Rome, Italy.
Siegbahn, Agneta, 1947- (author)
Uppsala universitet,Klinisk kemi
Storey, Robert F. (author)
Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England.
Vilahur, Gemma (author)
Hosp Santa Creu & Sant Pau, CiberCV, Cardiovasc Sci Inst ICCC IIB St Pau, Barcelona, Spain.
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Catholic Univ, Sch Med, Dept Pharmacol, Largo F Vito 1, I-00168 Rome, Italy Santo Andres Hosp, Div Cardiol, Leiria, Portugal. (creator_code:org_t)
Elsevier BV, 2017
2017
English.
In: Journal of the American College of Cardiology. - : Elsevier BV. - 0735-1097 .- 1558-3597. ; 70:14, s. 1760-1776
  • Research review (peer-reviewed)
Abstract Subject headings
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  • Antiplatelet drugs provide first-line antithrombotic therapy for the management of acute ischemic syndromes (both coronary and cerebrovascular) and for the prevention of their recurrence. Their role in the primary prevention of atherothrombosis remains controversial because of the uncertain balance of the potential benefits and risks when combined with other preventive strategies. The aim of this consensus document is to review the evidence for the efficacy and safety of antiplatelet drugs, and to provide practicing cardiologists with an updated instrument to guide their choice of the most appropriate antiplatelet strategy for the individual patient presenting with different clinical manifestations of coronary atherothrombosis, in light of comorbidities and/or interventional procedures.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

aspirin
cangrelor
clopidogrel
prasugrel
ticagrelor
vorapaxar

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