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The positive effects of habit reversal treatment of scratching in children with atopic dermatitis : a randomized controlled study

Norén, Peter (author)
Uppsala universitet,Dermatologi och venereologi
Hagströmer, L. (author)
Department of Dermatology, Södersjukhuset, Stockholm, Sweden
Alimohammadi, Mohammad (author)
Uppsala universitet,Dermatologi och venereologi
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Melin, Lennart, 1942- (author)
Uppsala universitet,Institutionen för psykologi,Laserkliniken Uppsala, Uppsala, Sweden
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 (creator_code:org_t)
2018-01-24
2018
English.
In: British Journal of Dermatology. - : Oxford University Press (OUP). - 0007-0963 .- 1365-2133. ; 178:3, s. 665-673
  • Journal article (peer-reviewed)
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  • Background: Scratching and itch are common clinical signs of atopic dermatitis (AD). Studies of adult patients have shown that a decrease in scratching behaviour results in regression of inflammation and improved healing of the skin.Objectives: To investigate whether a modified habit reversal (HR) treatment protocol could be used for the treatment of scratching in children to improve skin status.Methods: The study is a single‐blind, randomized controlled trial of 39 patients who started with registration a week before randomization into one of two groups (intervention or control). The participants in the intervention group received a habit‐breaking therapy of their scratching behaviour (i.e. HR) in addition to a potent steroid (mometasone furoate), whereas the patients in the control group received the steroid alone. The patients were assessed by an independent dermatologist after the first week of registration (baseline assessment) and then after 3 and 8 weeks of treatment. The primary efficacy variable was a change in objective Scoring Atopic Dermatitis (SCORAD).Results: At the end of the 3‐week treatment period, the change in mean objective SCORAD was significantly (P = 0·027) higher in the intervention group (−31·9 ± 9·5) than in the control group (−23·8 ± 10·1). After the 8‐week follow‐up, the change in mean objective SCORAD was significantly (P = 0·0038) higher in the intervention group (−31·7 ± 10·4) than in the control group (−19·7 ± 9·4).Conclusions: The treatment of scratching with the HR method in combination with a potent steroid was found to improve skin status significantly after 3 and 11 weeks.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)

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Norén, Peter
Hagströmer, L.
Alimohammadi, Mo ...
Melin, Lennart, ...
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MEDICAL AND HEALTH SCIENCES
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