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Dead space analysis...
Dead space analysis at different levels of positive end-expiratory pressure in acute respiratory distress syndrome patients
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- Gogniat, Emiliano (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Ducrey, Marcela (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Dianti, Jose (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Madorno, Matias (author)
- Inst Tecnol Buenos Aires ITBA, Buenos Aires, DF, Argentina
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- Roux, Nicolas (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Midley, Alejandro (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Raffo, Julio (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Giannasi, Sergio (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- San Roman, Eduardo (author)
- Hosp Italiano Buenos Aires, Dept Intens Care Med, Buenos Aires, DF, Argentina
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- Suarez-Sipmann, Fernando (author)
- Uppsala universitet,Anestesiologi och intensivvård,Hedenstiernalaboratoriet,CIBERES, Madrid, Spain;Hosp Univ & Politecn La Fe, Serv Med Intens, Valencia, Spain
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- Tusman, Gerardo (author)
- Hosp Privado Comunidad Mar Del Plata, Dept Anesthesiol, Mar Del Plata, Buenos Aires, Argentina
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(creator_code:org_t)
- W B SAUNDERS CO-ELSEVIER INC, 2018
- 2018
- English.
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In: Journal of critical care. - : W B SAUNDERS CO-ELSEVIER INC. - 0883-9441 .- 1557-8615. ; 45, s. 231-238
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Purpose: To analyze the effects of positive end-expiratory pressure (PEEP) on Bohr's dead space (VDBohr/VT) in patients with acute respiratory distress syndrome (ARDS).Material and methods: Fourteen ARDS patients under lung protective ventilation settingswere submitted to 4 different levels of PEEP (0, 6, 10, 16 cmH(2)O). Respiratory mechanics, hemodynamics and volumetric capnography were recorded at each protocol step.Results: Two groups of patients responded differently to PEEP when comparing baseline with 16-PEEP: those in which driving pressure increased > 15% (Delta P.(15%), n = 7, p = .016) and those in which the change was <= 15% (Delta P-<= 15%, n = 7, p = .700). VDBohr/VT was higher in Delta P-<= 15% than in Delta P-<= 15% patients at baseline ventilation [0.58 (0.49-0.60) vs 0.46 (0.43-0.46) p = .018], at 0-PEEP [0.50 (0.47-0.54) vs 0.41 (0.40-0.43) p = .012], at 6-PEEP [0.55 (0.49-0.57) vs 0.44 (0.42-0.45) p = .008], at 10-PEEP [0.59 (0.51-0.59) vs 0.45 (0.44-0.46) p = .006] and at 16-PEEP [0.61 (0.56-0.65) vs 0.47 (0.45-0.48) p =. 001]. We found a good correlation between Delta P and VDBohr/VT only in the Delta P.(15%) group (r = 0.74, p < .001).Conclusions: Increases in PEEP result in higher VDBohr/VT only when associated with an increase in driving pressure.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Keyword
- ARDS
- Volumetric capnography
- PEEP
- PACO(2)
- Dead space
- Carbon dioxide
Publication and Content Type
- ref (subject category)
- art (subject category)
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Gogniat, Emilian ...
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Ducrey, Marcela
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Dianti, Jose
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Madorno, Matias
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Roux, Nicolas
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Midley, Alejandr ...
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Raffo, Julio
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Giannasi, Sergio
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San Roman, Eduar ...
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Suarez-Sipmann, ...
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Tusman, Gerardo
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Anesthesiology a ...
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Journal of criti ...
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Uppsala University