Search: onr:"swepub:oai:DiVA.org:uu-361555" >
Auditory brainstem ...
-
Baghdassarian, EvaUppsala universitet,Psykiatri, Akademiska sjukhuset
(author)
Auditory brainstem response (ABR) profiling tests as diagnostic support for schizophrenia and adult attention-deficit hyperactivity disorder (ADHD)
- Article/chapterEnglish2018
Publisher, publication year, extent ...
-
2017-08-14
-
Cambridge University Press (CUP),2018
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-361555
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-361555URI
-
https://doi.org/10.1017/neu.2017.24DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Objective: To evaluate the performances of two auditory brainstem response (ABR) profiling tests as potential biomarkers and diagnostic support for schizophrenia and adult attention-deficit hyperactivity disorder (ADHD), respectively, in an investigator-initiated blinded study design.Method: Male and female patients with schizophrenia (n=26) and adult ADHD (n=24) meeting Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (DSM IV) diagnostic criteria and healthy controls (n=58) comprised the analysis set (n=108) of the total number of study participants (n=119). Coded sets of randomized ABR recordings were analysed by an independent party blinded to clinical diagnoses before a joint code-breaking session.Results: The ABR profiling test for schizophrenia identified schizophrenia patients versus controls with a sensitivity of 84.6% and a specificity of 93.1%. The ADHD test identified patients with adult ADHD versus controls with a sensitivity of 87.5% and a specificity of 91.4%.Conclusion: The ABR profiling tests discriminated schizophrenia and ADHD versus healthy controls with high sensitivity and specificity. The methods deserve to be further explored in larger clinical studies including a broad range of psychiatric disorders to determine their utility as potential diagnostic biomarkers.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Nilsson, Maria MarkhedUppsala universitet,Psykiatri, Akademiska sjukhuset(Swepub:uu)marni511
(author)
-
Lindström, EvaUppsala universitet,Psykiatri, Akademiska sjukhuset(Swepub:uu)evlin676
(author)
-
Nilsson, Björn M.Uppsala universitet,Psykiatri, Akademiska sjukhuset(Swepub:uu)bjornilss
(author)
-
Lewander, TommyUppsala universitet,Psykiatri, Akademiska sjukhuset(Swepub:uu)tommlewa
(author)
-
Uppsala universitetPsykiatri, Akademiska sjukhuset
(creator_code:org_t)
Related titles
-
In:Acta Neuropsychiatrica: Cambridge University Press (CUP)30:3, s. 137-1470924-27081601-5215
Internet link
Find in a library
To the university's database