The prevalence of chronic airflow obstruction in three cities in the Nordic-Baltic region

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Broström, ErikaUppsala universitet,Lung- allergi- och sömnforskning (author)

The prevalence of chronic airflow obstruction in three cities in the Nordic-Baltic region

Article/chapterEnglish2018

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Saunders Elsevier,2018
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LIBRIS-ID:oai:DiVA.org:uu-363418
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-363418URI
https://doi.org/10.1016/j.rmed.2018.08.007DOI

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Language:English
Summary in:English

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Subject category:art swepub-publicationtype

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Back ground: Chronic airflow obstruction (CAO) is the primary characteristic of Chronic obstructive pulmonary disease (COPD) but is also seen in chronic asthma. Objective: To compare the prevalence of CAO and possible risk factors between Tartu in Estonia, Reykjavik in Iceland and Uppsala in Sweden. Methods: All participants underwent spirometry testing of forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) before and after bronchodilation. CAO was defined as post-bronchodilator FEV1/FVC below lower limit of normal. Information on respiratory diseases and smoking status, was obtained through questionnaires administered by trained interviewers. Results: 1037 men and 956 women participated in the study. The prevalence of CAO was lower in women in Tartu compared to the other centres (4.9% vs. 13.4 and 8.7% in Reykjavik and Uppsala, respectively, p = 0.002) while no difference was found for men. A similar picture was seen for the proportion of participants that had smoked 10 pack years or more which was much lower in Tartu for women than in Reykjavik and Uppsala, respectively (13.2% vs. 33.7 and 29.2%, p < 0.001). (Fig. 1). Of the participants with CAO the majority (57-67%) did not have a previous diagnosis of asthma or COPD. Conclusion: The prevalence of CAO was lower in Estonian women than in women from Iceland and Sweden. The reason for this was probably that the Estonian women had smoked less than the female participants from Iceland and Sweden. The majority of those with CAO do not have a diagnosed lung disease.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Lungmedicin och allergi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Respiratory Medicine and Allergy hsv//eng
Chronic airflow obstruction
COPD
Asthma
Smoking
Gender difference

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Jogi, RainTartu Univ Hosp, Lung Clin, Tartu, Estonia(Swepub:uu)raijo735 (author)
Gislason, ThorarinnLandspitali Univ Hosp, Dept Sleep, Reykjavik, Iceland;Univ Iceland, Fac Med, Reykjavik, Iceland (author)
Benediktsdottir, BryndisUniv Iceland, Fac Med, Reykjavik, Iceland (author)
Burney, Peter G. J.Imperial Coll, Natl Heart & Lung Inst, London, England (author)
Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning,Imperial Coll, Natl Heart & Lung Inst, London, England(Swepub:uu)chrisjn (author)
Uppsala universitetLung- allergi- och sömnforskning (creator_code:org_t)

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In:Respiratory Medicine: Saunders Elsevier143, s. 8-130954-61111532-3064

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