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Health care resourc...
Health care resource utilization and cost for asthma patients regularly treated with oral corticosteroids - a Swedish observational cohort study (PACEHR)
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- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
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- Lisspers, Karin, Docent, 1954- (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Ställberg, Björn, Docent (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Johansson, Gunnar (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Telg, Gunilla (author)
- AstraZeneca Nord Baltic, Sodertalje, Sweden
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- Thuresson, Marcus (author)
- Statisticon AB, Uppsala, Sweden
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- Christensen, Helene Nordahl (author)
- AstraZeneca Nord Baltic, Sodertalje, Sweden
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- Larsson, Kjell (author)
- Karolinska Institutet,Karolinska Inst, Natl Inst Environm Med, Solna, Sweden
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(creator_code:org_t)
- 2018-09-03
- 2018
- English.
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In: Respiratory Research. - : BMC. - 1465-9921 .- 1465-993X. ; 19
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Abstract
Subject headings
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- Background: Patients with severe uncontrolled asthma may receive oral corticosteroid (OCS) treatment regularly. The present study investigated the health care resource utilization and cost in regularly OCS treated Swedish asthma patients.Methods: Primary care medical records data were linked to data from Swedish national health registries. Patients >= 18 years with a drug claim for obstructive pulmonary diseases during 2007-2009 (index date) and a prior asthma diagnosis, were classified by their OCS claims during the 12-months' post index period: regular OCS equals >= 5 mg per day; periodic OCS less than 5 mg per day; or non-OCS users. Cost of asthma-and OCS-morbidity-related health care resource utilization were calculated.Results: A total of 15,437 asthma patients (mean age 47.8, female 62.6%), whereof 223 (1.44%) were regular OCS users, 3054 (19.7%) were periodic, and 12,160 (78.7%) were non-OCS users. Regular OCS users were older and more often females, had lower lung function, greater eosinophil count and more co-morbidities at baseline compared with the other groups. Age-adjusted annual total health care cost was three-times greater in the regular OCS group ((sic)5615) compared with the non-OCS users ((SIC) 1980) and twice as high as in the periodic OCS group ((sic) 2948). The major cost driver in the non-OCS and periodic OCS groups were primary care consultations, whereas inpatient costs were the major cost driver in the regular OCS group. The asthma related costs represented 10-12% of the total cost in all three groups.Conclusion: In this real-life asthma study in Sweden, the total yearly cost of health care resource utilization for a regular OCS user was three times greater than for a patient with no OCS use, indicating substantial economic and health care burden for asthma patients on regular oral steroid treatment.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- Severe asthma
- Uncontrolled asthma
- Health care resource utilization
- Oral corticosteroids
- Cost
Publication and Content Type
- ref (subject category)
- art (subject category)
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