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Practice Patterns o...
Practice Patterns of Stereotactic Radiotherapy in Pediatrics : Results From an International Pediatric Research Consortium
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- Alcorn, Sara (author)
- Johns Hopkins Sch Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA
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- Nilsson, Kristina, 1967- (author)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Rao, Avani D. (author)
- Johns Hopkins Sch Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA
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- Ladra, Matthew M. (author)
- Johns Hopkins Sch Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA
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- Ermoian, Ralph P. (author)
- Univ Washington, Dept Radiat Oncol, Seattle, WA 98195 USA
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- Villar, Rosangela C. (author)
- Ctr Infantil Boldrini, Dept Radiat Oncol, Campinas, SP, Brazil
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- Chen, Michael J. (author)
- Grp Apoio Adolescente & Crianca Canc, Dept Radiat, Sao Paulo, Brazil
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- Kobyzeva, Daria (author)
- Fed Sci Clin Ctr Childrens Hematol Oncol & Immuno, Dept Radiotherapy, Moscow, Russia
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- Nechesnyuk, Alexey V. (author)
- Fed Sci Clin Ctr Childrens Hematol Oncol & Immuno, Dept Radiotherapy, Moscow, Russia
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- Ford, Eric (author)
- Univ Washington, Dept Radiat Oncol, Seattle, WA 98195 USA
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- MacDonald, Shannon (author)
- Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
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- Winey, Brian (author)
- Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
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- Dieckmann, Karin (author)
- Univ Klin Strahlentherapie & Strahlenbiol, Dept Radiat Oncol, Vienna, Austria
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- Terezakis, Stephanie A. (author)
- Johns Hopkins Sch Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA
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(creator_code:org_t)
- Lippincott Williams & Wilkins, 2018
- 2018
- English.
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In: Journal of pediatric hematology/oncology (Print). - : Lippincott Williams & Wilkins. - 1077-4114 .- 1536-3678. ; 40:7, s. 522-526
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Purpose/Objectives: There is little consensus regarding the application of stereotactic radiotherapy (SRT) in pediatrics. We evaluated patterns of pediatric SRT practice through an international research consortium. Materials and Methods: Eight international institutions with pediatric expertise completed a 124-item survey evaluating patterns of SRT use for patients 21 years old and younger. Frequencies of SRT use and median margins applied with and without SRT were evaluated. Results: Across institutions, 75% reported utilizing SRT in pediatrics. SRT was used in 22% of brain, 18% of spine, 16% of other bone, 16% of head and neck, and <1% of abdomen/pelvis, lung, and liver cases across sites. Of the hypofractionated SRT cases, 42% were delivered with definitive intent. Median gross tumor volume to planning target volume margins for SRT versus non-SRT plans were 0.2 versus 1.4 cm for brain, 0.3 versus 1.5 cm for spine/other bone, 0.3 versus 2.0 cm for abdomen/pelvis, 0.7 versus 1.5 cm for head and neck, 0.5 versus 1.7 cm for lung, and 0.5 versus 2.0 cm for liver sites. Conclusions: SRT is commonly utilized in pediatrics across a range of treatment sites. Margins used for SRT were substantially smaller than for non-SRT planning, highlighting the utility of this approach in reducing treatment volumes.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- pediatric stereotactic radiosurgery
- stereotactic radiosurgery
- stereotactic body radiation therapy
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Alcorn, Sara
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Nilsson, Kristin ...
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Rao, Avani D.
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Ladra, Matthew M ...
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Ermoian, Ralph P ...
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Villar, Rosangel ...
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show more...
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Chen, Michael J.
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Kobyzeva, Daria
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Nechesnyuk, Alex ...
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Ford, Eric
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MacDonald, Shann ...
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Winey, Brian
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Dieckmann, Karin
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Terezakis, Steph ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
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Uppsala University