Search: onr:"swepub:oai:DiVA.org:uu-369017" >
Lupus-related singl...
-
Bernatsky, SashaMcGill Univ, Ctr Hlth, Res Inst, Div Clin Epidemiol, Montreal, PQ, Canada
(author)
Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma
- Article/chapterEnglish2017
Publisher, publication year, extent ...
-
2017-11-12
-
BMJ,2017
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-369017
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-369017URI
-
https://doi.org/10.1136/lupus-2016-000187DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:229214033URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Objective: Determinants of the increased risk of diffuse large B-cell lymphoma (DLBCL) in SLE are unclear. Using data from a recent lymphoma genome-wide association study (GWAS), we assessed whether certain lupus-related single nucleotide polymorphisms (SNPs) were also associated with DLBCL. Methods: GWAS data on European Caucasians from the International Lymphoma Epidemiology Consortium (InterLymph) provided a total of 3857 DLBCL cases and 7666 general-population controls. Data were pooled in a random-effects meta-analysis. Results: Among the 28 SLE-related SNPs investigated, the two most convincingly associated with risk of DLBCL included the CD40 SLE risk allele rs4810485 on chromosome 20q13 (OR per risk allele=1.09, 95% CI 1.02 to 1.16, p=0.0134), and the HLA SLE risk allele rs1270942 on chromosome 6p21.33 (OR per risk allele=1.17, 95% CI 1.01 to 1.36, p=0.0362). Of additional possible interest were rs2205960 and rs12537284. The rs2205960 SNP, related to a cytokine of the tumour necrosis factor superfamily TNFSF4, was associated with an OR per risk allele of 1.07, 95% CI 1.00 to 1.16, p=0.0549. The OR for the rs12537284 (chromosome 7q32, IRF5 gene) risk allele was 1.08, 95% CI 0.99 to 1.18, p=0.0765. Conclusions: These data suggest several plausible genetic links between DLBCL and SLE.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Garcia, Hector A. VelasquezUniv British Columbia, BC Canc Res Ctr, Vancouver, BC, Canada;Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada
(author)
-
Spinelli, John J.Univ British Columbia, BC Canc Res Ctr, Vancouver, BC, Canada;Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada
(author)
-
Gaffney, PatrickOklahoma Med Res Fdn, Arthrit & Clin Immunol Res Program, 825 NE 13th St, Oklahoma City, OK 73104 USA
(author)
-
Smedby, Karin E.Karolinska Institutet
(author)
-
Ramsey-Goldman, RosalindNorthwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
(author)
-
Wang, Sophia S.Beckman Res Inst, Div Canc Etiol, Dept Populat Sci, Duarte, CA USA
(author)
-
Adami, Hans-OlovKarolinska Institutet
(author)
-
Albanes, DemetriusNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Angelucci, EmanueleOsped Oncol Riferimento Reg A Businco, Hematol Unit, Cagliari, Italy
(author)
-
Ansell, Stephen M.Mayo Clin, Dept Med, Rochester, MN USA
(author)
-
Asmann, Yan W.Mayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Jacksonville, FL 32224 USA
(author)
-
Becker, NikolausGerman Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
(author)
-
Benavente, YolandaCatalan Inst Oncol IDIBELL, Canc Epidemiol Res Programme, Barcelona, Spain
(author)
-
Berndt, Sonja I.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Bertrand, Kimberly A.Boston Univ, Slone Epidemiol Ctr, Boston, MA 02215 USA
(author)
-
Birmann, Brenda M.Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA;Harvard Med Sch, Boston, MA USA
(author)
-
Boeing, HeinerGerman Inst Human Nutr, Dept Epidemiol, Potsdam, Germany
(author)
-
Boffetta, PaoloIcahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA
(author)
-
Bracci, Paige M.Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
(author)
-
Brennan, PaulInt Agcy Res Canc, Lyon, France
(author)
-
Brooks-Wilson, Angela R.BC Canc Agcy, Genome Sci Ctr, Vancouver, BC, Canada
(author)
-
Cerhan, James R.Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
(author)
-
Chanock, Stephen J.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Clavel, JacquelineCtr Res Epidemiol & Stat Sorbonne Paris Cite CRES, INSERM, Epidemiol Childhood & Adolescent Canc Grp, Paris, France
(author)
-
Conde, LuciaUniv Alabama Birmingham, Sch Publ Hlth, Dept Epidemiol, Birmingham, AL 35294 USA;Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL 35294 USA
(author)
-
Cotenbader, Karen H.Brigham & Womens Hosp, Div Rheumatol Immunol & Allergy, 75 Francis St, Boston, MA 02115 USA
(author)
-
Cox, David G.Ctr Leon Berard, INSERM, Canc Res Ctr Lyon, U1052, Lyon, France
(author)
-
Cozen, WendyUniv Southern Calif, USC Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA
(author)
-
Crouch, SimonUniv York, Dept Hlth Sci, York, N Yorkshire, England
(author)
-
De Roos, Anneclaire J.Drexel Univ, Dornsife Sch Publ Hlth, Dept Environm & Occupat Hlth, Philadelphia, PA 19104 USA
(author)
-
de Sanjose, SilviaCatalan Inst Oncol IDIBELL, Canc Epidemiol Res Programme, Barcelona, Spain;CIBERESP, Barcelona, Spain
(author)
-
Di Lollo, SimonettaUniv Florence, Dept Surg & Translat Med, Sect Anatomopathol, Florence, Italy
(author)
-
Diver, W. RyanAmer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA
(author)
-
Dogan, AhmetMayo Clin, Dept Hlth Sci Res, Div Biomed Stat & Informat, Jacksonville, FL 32224 USA;Mem Sloan Kettering Canc Ctr, Dept Lab Med, 1275 York Ave, New York, NY 10021 USA;Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA
(author)
-
Foretova, LenkaMasaryk Mem Canc Inst, Dept Canc Epidemiol & Genet, Brno, Czech Republic;MF MU, Brno, Czech Republic
(author)
-
Ghesquieres, HerveCtr Leon Berard, Dept Hematol, Lyon, France
(author)
-
Giles, Graham G.Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia
(author)
-
Glimelius, BengtUppsala universitet,Experimentell och klinisk onkologi(Swepub:uu)bengglim
(author)
-
Habermann, Thomas M.Mayo Clin, Dept Med, Div Hematol, Rochester, MN USA
(author)
-
Haioun, CorinneHenri Mondor Hosp, Lymphoid Malignancies Unit, Creteil, France;Univ Paris Est, Creteil, France
(author)
-
Hartge, PatriciaNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Hjalgrim, HenrikStatens Serum Inst, Dept Epidemiol Res, Div Hlth Surveillance & Res, Copenhagen, Denmark
(author)
-
Holford, Theodore R.Yale Sch Publ Hlth, Dept Biostat, New Haven, CT USA
(author)
-
Holly, Elizabeth A.Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
(author)
-
Jackson, Rebecca D.Ohio State Univ, Div Endocrinol Diabet & Metab, Columbus, OH 43210 USA
(author)
-
Kaaks, RudolphGerman Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany
(author)
-
Kane, EleanorUniv York, Dept Hlth Sci, York, N Yorkshire, England
(author)
-
Kelly, Rachel S.Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA;Harvard Med Sch, Boston, MA USA
(author)
-
Klein, Robert J.Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, Icahn Inst Genom & Multiscale Biol, New York, NY 10029 USA
(author)
-
Kraft, PeterHarvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
(author)
-
Kricker, AnneUniv Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia
(author)
-
Lan, QingNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Lawrence, CharlesWestat Corp, Rockville, MD USA
(author)
-
Liebow, MarkMayo Clin, Dept Med, Rochester, MN USA
(author)
-
Lightfoot, TracyUniv York, Dept Hlth Sci, York, N Yorkshire, England
(author)
-
Link, Brian K.Univ Iowa, Dept Internal Med, Carver Coll Med, Iowa City, IA 52242 USA
(author)
-
Maynadie, MarcUniv Bourgogne Franche Comte, Registre Hemopathies Malignes Cote Or, EA 4184, Dijon, France;Dijon Univ Hosp, Dijon, France
(author)
-
Mckay, JamesInt Agcy Res Canc, Lyon, France
(author)
-
Melbye, MadsStatens Serum Inst, Dept Epidemiol Res, Div Hlth Surveillance & Res, Copenhagen, Denmark
(author)
-
Molina, Thierry J.Univ Paris 05, Sorbonne Paris Cite, Necker Enfants Malad, AP HP,Dept Pathol, Paris, France
(author)
-
Monnereau, AlainCtr Res Epidemiol & Stat Sorbonne Paris Cite CRES, INSERM, Epidemiol Childhood & Adolescent Canc Grp, Paris, France
(author)
-
Morton, Lindsay M.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Nieters, AlexandraUniv Med Ctr Freiburg, Ctr Chron Immunodeficiency, Freiburg, Germany
(author)
-
North, Kari E.Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27515 USA
(author)
-
Novak, Anne J.Mayo Clin, Dept Med, Rochester, MN USA
(author)
-
Offit, KennethMem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA
(author)
-
Purdue, Mark P.Ontario Hlth Study, Toronto, ON, Canada
(author)
-
Rais, MarcoUniv Cagliari, Dept Publ Hlth Clin & Mol Med, Monserrato, Italy
(author)
-
Riby, JacquesUniv Alabama Birmingham, Sch Publ Hlth, Dept Epidemiol, Birmingham, AL 35294 USA;Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL 35294 USA
(author)
-
Roman, EveUniv York, Dept Hlth Sci, York, N Yorkshire, England
(author)
-
Rothman, NathanielNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Salles, GillesHosp Civils Lyon, Dept Hematol, Pierre Benite, France
(author)
-
Severi, GianlucaHuman Genet Fdn, Turin, Italy
(author)
-
Severson, Richard K.Wayne State Univ, Dept Family Med & Publ Hlth Sci, Detroit, MI USA
(author)
-
Skibola, Christine F.Univ Alabama Birmingham, Sch Publ Hlth, Dept Epidemiol, Birmingham, AL 35294 USA;Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL 35294 USA
(author)
-
Slager, Susan L.Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
(author)
-
Smith, AlexUniv York, Dept Hlth Sci, York, N Yorkshire, England
(author)
-
Smith, Martyn T.Univ Calif Berkeley, Sch Publ Hlth, Div Environm Hlth Sci, Berkeley, CA 94720 USA
(author)
-
Southey, Melissa C.Univ Melbourne, Dept Pathol, Genet Epidemiol Lab, Melbourne, Vic, Australia
(author)
-
Staines, AnthonyDublin City Univ, Sch Nursing & Human Sci, Dublin, Ireland
(author)
-
Teras, Lauren R.Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA
(author)
-
Thompson, Carrie A.Mayo Clin, Dept Med, Rochester, MN USA
(author)
-
Tilly, HerveUniv Rouen, Ctr Heni Becquerel, Rouen, France
(author)
-
Tinker, Lesley F.Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1124 Columbia St, Seattle, WA 98104 USA
(author)
-
Tjonneland, AnneDanish Canc Soc, Res Ctr, Copenhagen, Denmark
(author)
-
Turner, JennyMacquarie Univ, Fac Med & Hlth Sci, Sydney, NSW, Australia
(author)
-
Vajdic, Claire M.Univ New South Wales, Ctr Big Data Res Hlth, Sydney, NSW, Australia
(author)
-
Vermeulen, Roel C. H.Univ Utrecht, Inst Risk Assessment Sci, Utrecht, Netherlands
(author)
-
Vijai, JosephMem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA
(author)
-
Vineis, PaoloImperial Coll London, Sch Publ Hlth, MRC PHE Ctr Environm & Hlth, London, England
(author)
-
Virtamo, JarmoNatl Inst Hlth & Welf, Chron Dis Prevent Unit, Helsinki, Finland
(author)
-
Wang, ZhaomingSt Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA
(author)
-
Weinstein, StephanieNCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
(author)
-
Witzig, Thomas E.Mayo Clin, Dept Med, Rochester, MN USA
(author)
-
Zelenetz, AndrewMem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA
(author)
-
Zeleniuch-Jacquotte, AnneNYU, Sch Med, Dept Populat Hlth, New York, NY USA
(author)
-
Zhang, YaweiYale Sch Publ Hlth, Dept Environm Hlth Sci, New Haven, CT USA
(author)
-
Zheng, TongzhangBrown Sch Publ Hlth, Dept Epidemiol, Providence, RI USA
(author)
-
Zucca, MariagraziaUniv Cagliari, Dept Biomed Sci, Monserrato, Italy
(author)
-
Clarke, Ann E.Univ Calgary, Div Rheumatol, Calgary, AB, Canada
(author)
-
McGill Univ, Ctr Hlth, Res Inst, Div Clin Epidemiol, Montreal, PQ, CanadaUniv British Columbia, BC Canc Res Ctr, Vancouver, BC, Canada;Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada
(creator_code:org_t)
Related titles
-
In:Lupus Science and Medicine: BMJ4:12053-8790
Internet link
Find in a library
To the university's database
- By the author/editor
-
Bernatsky, Sasha
-
Garcia, Hector A ...
-
Spinelli, John J ...
-
Gaffney, Patrick
-
Smedby, Karin E.
-
Ramsey-Goldman, ...
-
show more...
-
Wang, Sophia S.
-
Adami, Hans-Olov
-
Albanes, Demetri ...
-
Angelucci, Emanu ...
-
Ansell, Stephen ...
-
Asmann, Yan W.
-
Becker, Nikolaus
-
Benavente, Yolan ...
-
Berndt, Sonja I.
-
Bertrand, Kimber ...
-
Birmann, Brenda ...
-
Boeing, Heiner
-
Boffetta, Paolo
-
Bracci, Paige M.
-
Brennan, Paul
-
Brooks-Wilson, A ...
-
Cerhan, James R.
-
Chanock, Stephen ...
-
Clavel, Jacqueli ...
-
Conde, Lucia
-
Cotenbader, Kare ...
-
Cox, David G.
-
Cozen, Wendy
-
Crouch, Simon
-
De Roos, Annecla ...
-
de Sanjose, Silv ...
-
Di Lollo, Simone ...
-
Diver, W. Ryan
-
Dogan, Ahmet
-
Foretova, Lenka
-
Ghesquieres, Her ...
-
Giles, Graham G.
-
Glimelius, Bengt
-
Habermann, Thoma ...
-
Haioun, Corinne
-
Hartge, Patricia
-
Hjalgrim, Henrik
-
Holford, Theodor ...
-
Holly, Elizabeth ...
-
Jackson, Rebecca ...
-
Kaaks, Rudolph
-
Kane, Eleanor
-
Kelly, Rachel S.
-
Klein, Robert J.
-
Kraft, Peter
-
Kricker, Anne
-
Lan, Qing
-
Lawrence, Charle ...
-
Liebow, Mark
-
Lightfoot, Tracy
-
Link, Brian K.
-
Maynadie, Marc
-
Mckay, James
-
Melbye, Mads
-
Molina, Thierry ...
-
Monnereau, Alain
-
Morton, Lindsay ...
-
Nieters, Alexand ...
-
North, Kari E.
-
Novak, Anne J.
-
Offit, Kenneth
-
Purdue, Mark P.
-
Rais, Marco
-
Riby, Jacques
-
Roman, Eve
-
Rothman, Nathani ...
-
Salles, Gilles
-
Severi, Gianluca
-
Severson, Richar ...
-
Skibola, Christi ...
-
Slager, Susan L.
-
Smith, Alex
-
Smith, Martyn T.
-
Southey, Melissa ...
-
Staines, Anthony
-
Teras, Lauren R.
-
Thompson, Carrie ...
-
Tilly, Herve
-
Tinker, Lesley F ...
-
Tjonneland, Anne
-
Turner, Jenny
-
Vajdic, Claire M ...
-
Vermeulen, Roel ...
-
Vijai, Joseph
-
Vineis, Paolo
-
Virtamo, Jarmo
-
Wang, Zhaoming
-
Weinstein, Steph ...
-
Witzig, Thomas E ...
-
Zelenetz, Andrew
-
Zeleniuch-Jacquo ...
-
Zhang, Yawei
-
Zheng, Tongzhang
-
Zucca, Mariagraz ...
-
Clarke, Ann E.
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
Lupus Science an ...
- By the university
-
Uppsala University
-
Karolinska Institutet