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Unmet Needs in Appe...
Unmet Needs in Appendiceal Neuroendocrine Neoplasms
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- Toumpanakis, Christos (author)
- Royal Free Hosp, Neuroendocrine Tumour Unit, London, England
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- Fazio, Nicola (author)
- European Inst Oncol, Div Gastrointestinal Med Oncol & Neuroendocrine T, IEO, Milan, Italy
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- Tiensuu Janson, Eva (author)
- Uppsala universitet,Onkologisk endokrinologi
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- Hörsch, Dieter (author)
- Ctr Neuroendocrine Tumors Bad Berka, Bad Berka, Germany
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- Pascher, Andreas (author)
- Charite Univ Med Berlin, Campus Virchow Klinikum, Campus Charite Mitte, Dept Surg, Berlin, Germany
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- Reed, Nicholas (author)
- Gartnavel Royal Hosp, Beatson Oncol Ctr, Glasgow, Lanark, Scotland
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- O'Toole, Dermot (author)
- St James Hosp, Trinity Coll Dublin, Dept Clin Med, Dublin, Ireland
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- Nieveen van Dijkum, Els (author)
- Univ Amsterdam, Acad Med Ctr, Dept Surg, Amsterdam, Netherlands
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- Partelli, Stefano (author)
- Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Pancreas Translat & Clin Res Ctr, Pancreat Surg Unit, Milan, Italy
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- Rinke, Anja (author)
- UKGM, Dept Gastroenterol, Marburg, Germany
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- Kos-Kudla, Beata (author)
- Med Univ Silesia, Dept Pathophysiol & Endocrinol, Dept Endocrinol & Neuroendocrine Tumors, Katowice, Poland
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- Costa, Frederico (author)
- Hosp Sirio Libanes, Sao Paulo, Brazil
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- Pape, Ulrich-Frank (author)
- Charite Univ Med Berlin, Div Gastroenterol & Hepatol, Charite Campus Charite Mitte, Med Dept,Campus Virchow Klinikum, Berlin, Germany
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- Grozinsky-Glasberg, Simona (author)
- Hadassah Hebrew Univ, Med Ctr, Dept Endocrinol, Neuroendocrine Tumor Unit, Jerusalem, Israel
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- Scoazec, Jean-Yves (author)
- Gustave Roussy Canc Campus, Dept Pathol, Villejuif, France
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- Falkerby, Jenny (contributor)
- Uppsala universitet,Onkologisk endokrinologi
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- Sundin, Anders (contributor)
- Uppsala universitet,Radiologi
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- Tiensuu Janson, Eva (contributor)
- Uppsala universitet,Onkologisk endokrinologi
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- Welin, Staffan (contributor)
- Uppsala universitet,Onkologisk endokrinologi
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(creator_code:org_t)
- 2018-09-20
- 2019
- English.
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In: Neuroendocrinology. - : S. Karger AG. - 0028-3835 .- 1423-0194. ; 108:1, s. 37-44
- Related links:
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Abstract
Subject headings
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- Appendiceal neuroendocrine neoplasms (ANEN) are mostly discovered coincidentally during appendicectomy and usually have a benign clinical course; thus, appendicectomy alone is considered curative. However, in some cases, a malignant potential is suspected, and therefore additional operations such as completion right hemicolectomy are considered. The existing European Neuroendocrine Tumour Society (ENETS) guidelines provide useful data about epidemiology and prognosis, as well as practical recommendations with regards to the risk factors for a more aggressive disease course and the indications for a secondary operation. However, these guidelines are based on heterogeneous and retrospective studies. Therefore, the evidence does not seem to be robust, and there are still unmet needs in terms of accurate epidemiology and overall prognosis, optimal diagnostic and follow-up strategy, as well as identified risk factors that would indicate a more aggressive surgical approach at the beginning and a more intense follow-up. In this review, we are adopting a critical approach of the ENETS guidelines and published series for ANEN, focusing on the above-noted "grey areas".
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- Appendiceal neuroendocrine neoplasms
- Appendicectomy
- Appendix
- Carcinoids
- Right hemicolectomy
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Toumpanakis, Chr ...
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Fazio, Nicola
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Tiensuu Janson, ...
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Hörsch, Dieter
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Pascher, Andreas
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Reed, Nicholas
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O'Toole, Dermot
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Nieveen van Dijk ...
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Partelli, Stefan ...
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Rinke, Anja
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Kos-Kudla, Beata
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Costa, Frederico
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Pape, Ulrich-Fra ...
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Grozinsky-Glasbe ...
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Scoazec, Jean-Yv ...
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Falkerby, Jenny
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Sundin, Anders
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Welin, Staffan
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Neurosciences
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Neuroendocrinolo ...
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Uppsala University