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Liver fat :
Liver fat : a relevant target for dietary intervention? Summary of a Unilever workshop
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- Peters, Harry P. F. (author)
- Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands
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- Schrauwen, Patrick (author)
- Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Human Biol, Maastricht, Netherlands
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- Verhoef, Petra (author)
- Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands
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- Byrne, Christopher D. (author)
- Univ Southampton, Fac Med, Nutr & Metab, Southampton, Hants, England;Univ Hosp Southampton, Southampton Natl Inst Hlth Res, Biomed Res Ctr, Southampton, Hants, England
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- Mela, David J. (author)
- Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands
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- Pfeiffer, Andreas F. H. (author)
- Charite Univ Med Berlin, Dept Endocrinol Diabet & Nutr, Campus Benjamin Franklin, Berlin, Germany;German Inst Human Nutr, Dept Clin Nutr, Potsdam, Germany;DZD, German Ctr Diabet Res, Neuherberg, Germany
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- Risérus, Ulf, 1967- (author)
- Uppsala universitet,Klinisk nutrition och metabolism
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- Rosendaal, Frits R. (author)
- Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands
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- Schrauwen-Hinderling, Vera (author)
- Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Human Biol, Maastricht, Netherlands;Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Radiol, Maastricht, Netherlands
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(creator_code:org_t)
- 2017-05-08
- 2017
- English.
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In: Journal of Nutritional Science. - : CAMBRIDGE UNIV PRESS. - 2048-6790. ; 6
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Abstract
Subject headings
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- Currently it is estimated that about 1 billion people globally have non-alcoholic fatty liver disease (NAFLD), a condition in which liver fat exceeds 5 % of liver weight in the absence of significant alcohol intake. Due to the central role of the liver in metabolism, the prevalence of NAFLD is increasing in parallel with the prevalence of obesity, insulin resistance and other risk factors of metabolic diseases. However, the contribution of liver fat to the risk of type 2 diabetes mellitus and CVD, relative to other ectopic fat depots and to other risk markers, is unclear. Various studies have suggested that the accumulation of liver fat can be reduced or prevented via dietary changes. However, the amount of liver fat reduction that would be physiologically relevant, and the timeframes and dose-effect relationships for achieving this through different diet-based approaches, are unclear. Also, it is still uncertain whether the changes in liver fat per se or the associated metabolic changes are relevant. Furthermore, the methods available to measure liver fat, or even individual fatty acids, differ in sensitivity and reliability. The present report summarises key messages of presentations from different experts and related discussions from a workshop intended to capture current views and research gaps relating to the points above.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Keyword
- Liver fat
- Diet
- Type 2 diabetes
- Cardiovascular disease
Publication and Content Type
- ref (subject category)
- for (subject category)
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