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Best Practices Reco...
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Yatabe, YasushiAichi Canc Ctr, Dept Pathol & Mol Diagnost, Nagoya, Aichi, Japan
(author)
Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer
- Article/chapterEnglish2019
Publisher, publication year, extent ...
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Elsevier BV,2019
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-379023
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-379023URI
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https://doi.org/10.1016/j.jtho.2018.12.005DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Since the 2015 WHO classification was introduced into clinical practice, immunohistochemistry (IHC) has figured prominently in lung cancer diagnosis. In addition to distinction of small cell versus non-small cell carcinoma, patients' treatment of choice is directly linked to histologic subtypes of non-small cell carcinoma, which pertains to IHC results, particularly for poorly differentiated tumors. The use of IHC has improved diagnostic accuracy in the classification of lung carcinoma, but the interpretation of IHC results remains challenging in some instances. Also, pathologists must be aware of many interpretation pitfalls, and the use of IHC should be efficient to spare the tissue for molecular testing. The International Association for the Study of Lung Cancer Pathology Committee received questions on practical application and interpretation of IHC in lung cancer diagnosis. After discussions in several International Association for the Study of Lung Cancer Pathology Committee meetings, the issues and caveats were summarized in terms of 11 key questions covering common and important diagnostic situations in a daily clinical practice with some relevant challenging queries. The questions cover topics such as the best IHC markers for distinguishing NSCLC subtypes, differences in thyroid transcription factor 1 clones, and the utility of IHC in diagnosing uncommon subtypes of lung cancer and distinguishing primary from metastatic tumors. This article provides answers and explanations for the key questions about the use of IHC in diagnosis of lung carcinoma, representing viewpoints of experts in thoracic pathology that should assist the community in the appropriate use of IHC in diagnostic pathology.
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Added entries (persons, corporate bodies, meetings, titles ...)
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Dacic, SanjaUniv Pittsburgh, Dept Pathol, Pittsburgh, PA USA
(author)
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Borczuk, Alain C.Weill Cornell Med, Dept Pathol, New York, NY USA
(author)
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Warth, ArneInst Pathol Cytopathol & Mol Pathol MVZ UEGP Gies, Wetzlar, Limburg, Germany
(author)
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Russell, Prudence A.St Vincents Hosp, Dept Anat Pathol, Fitzroy, Vic, Australia;Univ Melbourne, Fitzroy, Vic, Australia
(author)
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Lantuejoul, SylvieGrenoble Alpes Univ, Dept Biopathol, Ctr Leon Berard, Lyon, France
(author)
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Beasley, Mary BethMt Sinai Med Ctr, Dept Pathol, New York, NY 10029 USA
(author)
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Thunnissen, ErikVrije Univ Amsterdam Med Ctr, Dept Pathol, Amsterdam, Netherlands
(author)
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Pelosi, GiuseppeUniv Milan, Dept Oncol & Hematooncol, Milan, Italy;IRCCS MultiMed, Milan, Italy
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Rekhtman, NatashaMem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA
(author)
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Bubendorf, LukasUniv Hosp Basel, Inst Pathol, Basel, Switzerland
(author)
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Mino-Kenudson, MariMassachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA;Harvard Med Sch, Boston, MA 02115 USA
(author)
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Yoshida, AkihikoNatl Canc Ctr, Dept Pathol & Clin Labs, Tokyo, Japan
(author)
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Geisinger, Kim R.Univ Mississippi, Med Ctr, Dept Pathol, Jackson, MS 39216 USA
(author)
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Noguchi, MasayukiUniv Tsukuba, Inst Basic Med Sci, Dept Pathol, Tsukuba, Ibaraki, Japan
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Chirieac, Lucian R.Harvard Med Sch, Boston, MA 02115 USA;Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA
(author)
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Botling, JohanUppsala universitet,Klinisk och experimentell patologi,Science for Life Laboratory, SciLifeLab,Johan Botling(Swepub:uu)johanbot
(author)
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Chung, Jin-HaengSeoul Natl Univ, Bundang Hosp, Dept Pathol, Seongnam City, Gyeonggi Do, South Korea;Seoul Natl Univ, Bundang Hosp, Resp Ctr, Seongnam City, Gyeonggi Do, South Korea
(author)
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Chou, Teh-YingTaipei Vet Gen Hosp, Div Mol Pathol, Dept Pathol & Lab Med, Taipei, Taiwan
(author)
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Chen, GangFudan Univ, Dept Pathol, Zhongshan Hosp, Shanghai, Peoples R China
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Poleri, ClaudiaOff Pathol Consultants, Buenos Aires, DF, Argentina
(author)
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Lopez-Rios, FernandoHosp Univ HM Sanchinarro, Lab Dianas Terapeut, Madrid, Spain
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Papotti, MauroUniv Turin, Dept Oncol, Turin, Italy
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Sholl, Lynette M.Harvard Med Sch, Boston, MA 02115 USA;Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA
(author)
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Roden, Anja C.Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA
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Travis, William D.Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA
(author)
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Hirsch, Fred R.Univ Colorado, Anschutz Med Campus, Aurora, CO USA
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Kerr, Keith M.Univ Aberdeen, Sch Med, Dept Pathol, Aberdeen Royal Infirm, Aberdeen, Scotland
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Tsao, Ming-SoundUniv Toronto, Dept Pathol, Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada
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Nicholson, Andrew G.Imperial Coll, Dept Histopathol, Royal Brompton & Harefield Natl Hlth Serv Fdn Tru, London, England;Imperial Coll, Natl Heart & Lung Inst, London, England
(author)
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Wistuba, IgnacioUniv Texas MD Anderson Canc Ctr, Dept Translat Mol Pathol, Houston, TX 77030 USA
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Moreira, Andre L.New York Univ Langone Hlth, Dept Pathol, New York, NY USA
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Aichi Canc Ctr, Dept Pathol & Mol Diagnost, Nagoya, Aichi, JapanUniv Pittsburgh, Dept Pathol, Pittsburgh, PA USA
(creator_code:org_t)
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In:Journal of Thoracic Oncology: Elsevier BV14:3, s. 377-4071556-08641556-1380
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Yatabe, Yasushi
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Dacic, Sanja
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Borczuk, Alain C ...
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Warth, Arne
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Russell, Prudenc ...
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Lantuejoul, Sylv ...
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Beasley, Mary Be ...
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Thunnissen, Erik
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Pelosi, Giuseppe
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Rekhtman, Natash ...
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Bubendorf, Lukas
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Mino-Kenudson, M ...
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Yoshida, Akihiko
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Geisinger, Kim R ...
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Noguchi, Masayuk ...
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Chirieac, Lucian ...
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Botling, Johan
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Chung, Jin-Haeng
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Chou, Teh-Ying
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Chen, Gang
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Poleri, Claudia
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Lopez-Rios, Fern ...
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Papotti, Mauro
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Sholl, Lynette M ...
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Roden, Anja C.
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Travis, William ...
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Hirsch, Fred R.
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Kerr, Keith M.
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Tsao, Ming-Sound
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Nicholson, Andre ...
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Wistuba, Ignacio
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Moreira, Andre L ...
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