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Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia

Chartomatsidou, Elisavet (author): Ctr Res & Technol Hellas, Inst Appl Biosci, 6th Km Charilaou Thermi Rd, GR-57001 Thessaloniki, Greece;Univ Ioannina, Dept Biol Applicat & Technol, Ioannina, Greece

Ntoufa, Stavroula (author): Ctr Res & Technol Hellas, Inst Appl Biosci, 6th Km Charilaou Thermi Rd, GR-57001 Thessaloniki, Greece

Kotta, Konstantia (author): Ctr Res & Technol Hellas, Inst Appl Biosci, 6th Km Charilaou Thermi Rd, GR-57001 Thessaloniki, Greece

Rovida, Alessandra (author): Univ Vita Salute San Raffaele, Div Expt Oncol, Strateg Res Program CLL & B Cell Neoplasia Unit, Milan, Italy;IRCCS Ist Sci San Raffaele, Milan, Italy

Akritidou, Maria Anna (author): Ctr Res & Technol Hellas, Inst Appl Biosci, 6th Km Charilaou Thermi Rd, GR-57001 Thessaloniki, Greece;Univ Ioannina, Dept Biol Applicat & Technol, Ioannina, Greece

Belloni, Daniela (author): Univ Vita Salute San Raffaele, Div Expt Oncol, Strateg Res Program CLL & B Cell Neoplasia Unit, Milan, Italy;IRCCS Ist Sci San Raffaele, Milan, Italy

Ferrero, Elisabetta (author): Univ Vita Salute San Raffaele, Div Expt Oncol, Strateg Res Program CLL & B Cell Neoplasia Unit, Milan, Italy;IRCCS Ist Sci San Raffaele, Milan, Italy

Trangas, Theoni (author): Univ Ioannina, Dept Biol Applicat & Technol, Ioannina, Greece

Stavroyianni, Niki (author): G Papanicolaou Hosp, BMT Unit, Dept Hematol, Thessaloniki, Greece

Anagnostopoulos, Achilles (author): G Papanicolaou Hosp, BMT Unit, Dept Hematol, Thessaloniki, Greece

Rosenquist, Richard (author): Karolinska Institutet,Uppsala universitet,Experimentell och klinisk onkologi,Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden

Ghia, Paolo (author): Univ Vita Salute San Raffaele, Div Expt Oncol, Strateg Res Program CLL & B Cell Neoplasia Unit, Milan, Italy;IRCCS Ist Sci San Raffaele, Milan, Italy

Papakonstantinou, Nikos (author): Ctr Res & Technol Hellas, Inst Appl Biosci, 6th Km Charilaou Thermi Rd, GR-57001 Thessaloniki, Greece

Stamatopoulos, Kostas (author): Ctr Res & Technol Hellas, Inst Appl Biosci, 6th Km Charilaou Thermi Rd, GR-57001 Thessaloniki, Greece

(creator_code:org_t)

2019-06-21
2019
English.
In: Blood Advances. - : AMER SOC HEMATOLOGY. - 2473-9529 .- 2473-9537. ; 3:12, s. 1891-1896

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Journal article (peer-reviewed)

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Key Points:Microenvironmental stimuli affect EZH2 expression and function in CLL.Combined B-cell signaling and EZH2 inhibition showed synergistic effects on primary CLL cells.

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By the author/editor: Chartomatsidou, ...; Ntoufa, Stavroul ...; Kotta, Konstanti ...; Rovida, Alessand ...; Akritidou, Maria ...; Belloni, Daniela; show more...; Ferrero, Elisabe ...; Trangas, Theoni; Stavroyianni, Ni ...; Anagnostopoulos, ...; Rosenquist, Rich ...; Ghia, Paolo; Papakonstantinou ...; Stamatopoulos, K ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Hematology

Articles in the publication: Blood Advances

By the university: Uppsala University; Karolinska Institutet

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