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Good Agreement Betw...
Good Agreement Between Hba1c Analyzed Using Capillary Electrophoresis, HPLC, Immunological and Enzymatic Methods
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- Rollborn, Niclas (author)
- Uppsala universitet,Klinisk kemi
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- Nordin, Gunnar (author)
- Equalis, Uppsala, Sweden
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- Mandic-Havelka, Aleksandra (author)
- Department of Molecular Medicine and Surgery, Karolinska Institute, Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden
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- Lohmander, Maria (author)
- Laboratory Medicine, Norra Älvsborgs Länssjukhus NÄL,Uddevalla Hospital, Uddevalla, Sweden
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- Elmgren, Anders (author)
- Laboratory of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Sisowath, Christin (author)
- Department of Molecular Medicine and Surgery, Karolinska Institute, Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden
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- Åkerfeldt, Torbjörn (author)
- Uppsala universitet,Klinisk kemi
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- Larsson, Benny (author)
- Department of Clinical Chemistry, Skåne University Hospital, Malmö, Sweden
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- Vallée, Maria (author)
- Laboratory Medicine Dalarna, Falun, Sweden
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- Hansson, Lars-Olof (author)
- Uppsala universitet,Klinisk kemi
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- Larsson, Anders (author)
- Uppsala universitet,Klinisk kemi
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(creator_code:org_t)
- 2019
- 2019
- English.
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In: Journal of Diabetes, Metabolism and its Complications. ; 1:1, s. 1-7
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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Abstract
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- Purpose: Hemoglobin A1c (HbA1c) is an essential marker for assessment of glycemic control in diabetes patients. The aim of this study was to evaluate the agreement between different HbA1c methods.Methodology: We used blood samples to compare HbA1c results analyzed with Capillarys 3 Tera, Roche Tina-Quant HbA1c Gen 3, BioRad Variant II Turbo (3 sites), Mono S® and Abbott Architect enzymatic method. The comparisons were made as paired instrument comparisons with Capillarys 3 Tera.Results: The linear correlations between the HbA1c methods were as follows:Cobas 6000 = 0.982 x Capillarys 3 Tera + 0.975, R² = 0.994;Architect c8000 = 0.982 x Capillarys 3 Tera + 1.064, R² = 0.994; Mono S® = 0.916 x Capillarys 3 Tera + 3.397, R² = 0.965;BioRad Variant II Turbo = 0.923 x Capillarys 3 Tera + 4.062, R² = 0.990; Tosoh G8 = 0.963 x Capillarys 3 Tera + 3.895, R² = 0.996.Conclusions: The different instrument platforms showed the best agreement in the 50-70 mmol/mol interval. Above and below this range the methods separated into 2 groups, one consisting of Capillarys 3 Tera, Roche Tina-Quant and Abbott enzymatic method and the other group consisting of BioRad Variant II Turbo, Tosoh G8 and Mono S®.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Rollborn, Niclas
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Nordin, Gunnar
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Mandic-Havelka, ...
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Lohmander, Maria
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Elmgren, Anders
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Sisowath, Christ ...
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Åkerfeldt, Torbj ...
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Larsson, Benny
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Vallée, Maria
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Hansson, Lars-Ol ...
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Larsson, Anders
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Clinical Laborat ...
- Articles in the publication
- Journal of Diabe ...
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Uppsala University