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Recurrent convergen...
Recurrent convergent evolution at amino acid residue 261 in fish rhodopsin
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- Hill, Jason (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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- Enbody, Erik D. (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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- Pettersson, Mats (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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- Sprehn, Charlotte Grace (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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- Bekkevold, Dorte (author)
- Tech Univ Denmark, Natl Inst Aquat Resources, DK-8600 Silkeborg, Denmark
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- Folkvord, Arild (author)
- Univ Bergen, Dept Biol Sci, N-5020 Bergen, Norway;Inst Marine Res, N-5018 Bergen, Norway
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- Laikre, Linda (author)
- Stockholms universitet,Zoologiska institutionen,Stockholm Univ, Div Populat Genet, Dept Zool, SE-10691 Stockholm, Sweden
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- Kleinau, Gunnar (author)
- Charite Univ Med Berlin, Inst Med Phys & Biophys, Grp Prot Xray Crystallog & Signal Transduct, Charitepl 1, D-10117 Berlin, Germany;Free Univ Berlin, Charitepl 1, D-10117 Berlin, Germany;Humboldt Univ, Charitepl 1, D-10117 Berlin, Germany;Berlin Inst Hlth, Charitepl 1, D-10117 Berlin, Germany
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- Scheerer, Patrick (author)
- Charite Univ Med Berlin, Inst Med Phys & Biophys, Grp Prot Xray Crystallog & Signal Transduct, Charitepl 1, D-10117 Berlin, Germany;Free Univ Berlin, Charitepl 1, D-10117 Berlin, Germany;Humboldt Univ, Charitepl 1, D-10117 Berlin, Germany;Berlin Inst Hlth, Charitepl 1, D-10117 Berlin, Germany
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- Andersson, Leif (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Swedish Univ Agr Sci, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden;Texas A&M Univ, Dept Vet Integrat Biosci, College Stn, TX 77843 USA,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics,Uppsala University,Texas A&M University
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(creator_code:org_t)
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- 2019-08-26
- 2019
- English.
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In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 116:37, s. 18473-18478
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Abstract
Subject headings
Close
- The evolutionary process that occurs when a species colonizes a new environment provides an opportunity to explore the mechanisms underlying genetic adaptation, which is essential knowledge for understanding evolution and the maintenance of biodiversity. Atlantic herring has an estimated total breeding stock of about 1 trillion (10(12)) and has colonized the brackish Baltic Sea within the last 10,000 y. Minute genetic differentiation between Atlantic and Baltic herring populations at selectively neutral loci combined with this rapid adaptation to a new environment facilitated the identification of hundreds of loci underlying ecological adaptation. A major question in the field of evolutionary biology is to what extent such an adaptive process involves selection of novel mutations with large effects or genetic changes at many loci, each with a small effect on phenotype (i.e., selection on standing genetic variation). Here we show that a missense mutation in rhodopsin (Phe261Tyr) is an adaptation to the red-shifted Baltic Sea light environment. The transition from phenylalanine to tyrosine differs only by the presence of a hydroxyl moiety in the latter, but this results in an up to 10-nm red-shifted light absorbance of the receptor. Remarkably, an examination of the rhodopsin sequences from 2,056 species of fish revealed that the same missense mutation has occurred independently and been selected for during at least 20 transitions between light environments across all fish. Our results provide a spectacular example of convergent evolution and how a single amino acid change can have a major effect on ecological adaptation.
Subject headings
- LANTBRUKSVETENSKAPER -- Bioteknologi med applikationer på växter och djur -- Genetik och förädling inom lantbruksvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agricultural Biotechnology -- Genetics and Breeding in Agricultural Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Keyword
- adaptation
- selective sweep
- convergent evolution
- natural selection
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Hill, Jason
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Enbody, Erik D.
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Pettersson, Mats
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Sprehn, Charlott ...
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Bekkevold, Dorte
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Folkvord, Arild
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show more...
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Laikre, Linda
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Kleinau, Gunnar
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Scheerer, Patric ...
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Andersson, Leif
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- About the subject
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- AGRICULTURAL SCIENCES
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AGRICULTURAL SCI ...
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and Agricultural Bio ...
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and Genetics and Bre ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Genetics
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Evolutionary Bio ...
- Articles in the publication
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Proceedings of t ...
- By the university
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Uppsala University
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Stockholm University
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Swedish University of Agricultural Sciences