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Buchwald Hartwig diversification of unprotected halotryptophans, halotryptophan containing tripeptides and the natural product barettin in aqueous conditions
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- Renault, Yohann J. G. (author)
- Univ St Andrews, Dept Chem, St Andrews KY16 9ST, Fife, Scotland;Univ St Andrews, BSRC, St Andrews KY16 9ST, Fife, Scotland
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- Lynch, Rosemary (author)
- Univ St Andrews, Dept Chem, St Andrews KY16 9ST, Fife, Scotland;Univ St Andrews, BSRC, St Andrews KY16 9ST, Fife, Scotland
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- Marelli, Enrico (author)
- Univ St Andrews, Dept Chem, St Andrews KY16 9ST, Fife, Scotland;Univ St Andrews, BSRC, St Andrews KY16 9ST, Fife, Scotland
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- (creator_code:org_t)
- 2019
- 2019
- English.
- In: Chemical Communications. - : ROYAL SOC CHEMISTRY. - 1359-7345 .- 1364-548X. ; 55:91, s. 13653-13656
- Journal article (peer-reviewed)
Abstract
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- Blending synthetic biology and synthetic chemistry represents a powerful approach to diversity complex molecules. To further enable this, compatible synthetic tools are needed. We report the first Buchwald Hartwig amination reactions with unprotected halo-tryptophans under aqueous conditions and demonstrate this methodology is applicable also to the modification of unprotected tripeptides and the natural product barettin.
Subject headings
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
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- ref (subject category)
- art (subject category)
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- Uppsala University
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