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Group and Single Ho...
Group and Single Housing of Male Mice : Collected Experiences from Research Facilities in Sweden
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- Zidar, Josefina (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,SCAW Nationellt centrum för djurvälfärd
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- Weber, Elin (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjurens miljö och hälsa (HMH),Department of Animal Environment and Health
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- Ewaldsson, Birgit (author)
- AstraZeneca, Dept Anim Sci & Technol, S-43183 Mölndal, Sweden
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- Tjäder, Solveig (author)
- Uppsala universitet,Institutionen för medicinsk cellbiologi,Uppsala Universitet, Centrum för försöksdjursverksamhet
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- Lilja, Josefin (author)
- Karolinska Inst, Dept Comparat Med, S-17177 Stockholm, Sweden
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- Mount, James (author)
- Swedish Med Prod Agcy, Dept Pharmaceut Safety, S-75103 Uppsala, Sweden
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- Svensson, Camilla I. (author)
- Karolinska Institutet,Karolinska Inst, Ctr Mol Med, Dept Physiol & Pharmacol, S-17177 Stockholm, Sweden
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- Svensk, Emma (author)
- Swedish Board Agr, Swedish 3Rs Ctr, S-55182 Jönköping, Sweden
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- Udén, Eva (author)
- Swedish Board Agr, Swedish 3Rs Ctr, S-55182 Jönköping, Sweden
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- Törnqvist, Elin (author)
- Karolinska Institutet,Swedish Board Agr, Swedish Natl Comm Protect Anim Used Sci Purposes, S-55182 Jönköping, Sweden;Karolinska Inst, Dept Integrat Toxicol, S-17177 Stockholm, Sweden
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- 2019-11-21
- 2019
- English.
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In: Animals. - : MDPI AG. - 2076-2615. ; 9:12
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https://doi.org/10.3...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Subject headings
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- Animals used for scientific purposes are protected by EU legislation. Social animals should be kept in stable groups that enable species-typical social behavior and provide individuals with social comfort. However, when group-housing male mice, aggression within the homecage is a common husbandry and welfare problem. Excessive fighting and injuries due to aggression can cause pain and stress, resulting in individuals being euthanized or housed individually. In addition, stress can alter physiological parameters, risking scientific validity and generating larger sample sizes. Mouse aggression, and the consequences thereof, thus opposes the 3R goals of Refining the methods to minimize potential pain and suffering and Reducing the number of animals used. Animal technicians, veterinarians, and scientists using animals have valuable information on how these problems are experienced and handled in practice. We assembled these experiences from laboratory animal facilities in Sweden, mapping problems observed and identifying strategies used to prevent mouse aggression. In line with current literature, less aggression was perceived if mice were grouped before sexual maturity, re-grouping avoided and nesting material transferred at cage cleaning. Preventing aggression will minimize pain and suffering and enable housing of stable groups, leading to more reliable scientific outcomes and is thus of high 3Rs relevance.
Subject headings
- NATURVETENSKAP -- Biologi -- Etologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Behavioural Sciences Biology (hsv//eng)
- LANTBRUKSVETENSKAPER -- Husdjursvetenskap -- Husdjursvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Animal and Dairy Sience -- Animal and Dairy Science. (hsv//eng)
Keyword
- aggression
- animal welfare
- laboratory animals
- male mice
- group housing
- 3R
- single housing
Publication and Content Type
- ref (subject category)
- art (subject category)
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Animals
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To the university's database
- By the author/editor
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Zidar, Josefina
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Weber, Elin
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Ewaldsson, Birgi ...
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Tjäder, Solveig
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Lilja, Josefin
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Mount, James
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show more...
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Svensson, Camill ...
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Svensk, Emma
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Udén, Eva
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Törnqvist, Elin
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Behavioural Scie ...
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- AGRICULTURAL SCIENCES
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AGRICULTURAL SCI ...
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and Animal and Dairy ...
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and Animal and Dairy ...
- Articles in the publication
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Animals
- By the university
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Uppsala University
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Karolinska Institutet
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Swedish University of Agricultural Sciences