Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

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d'Alessandro, ElisaMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)

Thrombo-Inflammation in Cardiovascular Disease : An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

Article/chapterEnglish2020

Publisher, publication year, extent ...

2020-04-14
Georg Thieme Verlag KG,2020
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:uu-411227
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-411227URI
https://doi.org/10.1055/s-0040-1708035DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:143537569URI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Thrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The third Maastricht Consensus Conference on Thrombosis assembled basic, translational, and clinical scientists to discuss the origin and potential consequences of thrombo-inflammation in the etiology, diagnostics, and management of patients with cardiovascular disease, including myocardial infarction, stroke, and peripheral artery disease. This article presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following topics: (1) challenges of the endothelial cell barrier; (2) circulating cells and thrombo-inflammation, focused on platelets, neutrophils, and neutrophil extracellular traps; (3) procoagulant mechanisms; (4) arterial vascular changes in atherogenesis; attenuating atherosclerosis and ischemia/reperfusion injury; (5) management of patients with arterial vascular disease; and (6) pathogenesis of venous thrombosis and late consequences of venous thromboembolism.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
thrombosis
inflammation
coagulation
pulmonary embolism
myocardial infarction
stroke
platelets

Added entries (persons, corporate bodies, meetings, titles ...)

Becker, ChristianJohannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Dermatol, Mainz, Germany. (author)
Bergmeier, WolfgangUniv N Carolina, Dept Biochem & Biophys, McAllister Heart Inst, Chapel Hill, NC 27515 USA. (author)
Bode, ChristophUniv Freiburg, Univ Heart Ctr Freiburg, Dept Cardiol & Angiol 1, Med Ctr, Bad Krozingen, Germany. (author)
Bourne, Joshua H.Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England. (author)
Brown, HelenaDFG Forschungszentrum Expt Biomed, Rudolf Virchov Zentrum, Wurzburg, Germany. (author)
Buller, Harry R.Univ Amsterdam, Med Ctr, Dept Vasc Med, Amsterdam, Netherlands. (author)
ten Cate-Hoek, Arina J.Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA. (author)
ten Cate, VincentJohannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Thrombosis & Hemostasis, Clin Epidemiol & Syst Med, Mainz, Germany. (author)
van Cauteren, Yvonne J. M.CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands. (author)
Cheung, Yam F. H.Leibniz Inst Analyt Wissensch ISAS, Dortmund, Germany. (author)
Cleuren, AudreyUniv Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA. (author)
Coenen, DanielleCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Crijns, Harry J. G. M.CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands. (author)
de Simone, IlariaCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Dolleman, Sophie C.Leiden Univ, Med Ctr, Dept Internal Med Nephrol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Einthoven Lab Expt Vasc & Regenerat Med, Leiden, Netherlands. (author)
Klein, Christine EspinolaJohannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Cardiol Cardiol 1, Mainz, Germany. (author)
Fernandez, Delia I.CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Granneman, LianneUniv Med Ctr Utrecht, Dept Clin Chem & Haematol, Utrecht, Netherlands. (author)
van t Hof, ArnoudCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands.;Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA. (author)
Henke, PeterMichigan Med Vasc Surg Clin, Ctr Cardiovasc, Ann Arbor, MI USA. (author)
Henskens, Yvonne M. C.CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Cent Diagnost Lab, Maastricht, Netherlands. (author)
Huang, JingnanCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Jennings, Lisa K.CirQuest Labs LLC, Memphis, TN USA.;Univ Tennessee, Ctr Hlth Sci, Memphis, TN 38163 USA. (author)
Jooss, NatalieCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Karel, MiekeCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
van den Kerkhof, DaniqueCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Klok, Frederik A.Leiden Univ, Med Ctr, Dept Thrombosis & Hemostasis, Leiden, Netherlands. (author)
Kremers, BramMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
Laemmle, BernhardUniv Bern, Bern Univ Hosp, Dept Hematol, Inselspital, Bern, Switzerland.;Univ Bern, Bern Univ Hosp, Cent Hematol Lab, Inselspital, Bern, Switzerland.;Johannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Thrombosis & Hemostasis, Mainz, Germany.;UCL, Haemostasis Res Unit, London, England. (author)
Leader, AviMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Rabin Med Ctr, Dept Hematol, Petah Tiqwa, Israel. (author)
Lundstrom, AnnikaKarolinska Institutet (author)
Mackman, NigelUniv N Carolina, UNC McAllister Heart Inst, Dept Med, Chapel Hill, NC 27515 USA. (author)
Mannucci, Pier M.IRCCS Ca Granda Maggiore Policlin Hosp Fdn, Sci Direct, Milan, Italy. (author)
Maqsood, ZahraDFG Forschungszentrum Expt Biomed, Rudolf Virchov Zentrum, Wurzburg, Germany. (author)
van der Meijden, Paola E. J.Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
van Moorsel, MarcUniv Med Ctr Utrecht, Dept Clin Chem & Haematol, Utrecht, Netherlands. (author)
Moran, Luis A.Univ Santiago de Compostela, CIMUS, Santiago De Compostela, Spain. (author)
Morser, JohnStanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA. (author)
van Mourik, ManoukCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands. (author)
Navarro, StefanoDFG Forschungszentrum Expt Biomed, Rudolf Virchov Zentrum, Wurzburg, Germany. (author)
Neagoe, Raluca A. I.Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England. (author)
Olie, Renske H.Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
van Paridon, PaulineMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
Posma, JensMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
Provenzale, IsabellaCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Reitsma, Pieter H.Leiden Univ, Med Ctr, Dept Internal Med Nephrol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Einthoven Lab Expt Vasc & Regenerat Med, Leiden, Netherlands. (author)
Scaf, BillyMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
Schurgers, LeonCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Seelig, JaapMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Rijnstate Ziekenhuis, Dept Cardiol, Arnhem, Netherlands. (author)
Siegbahn, Agneta,1947-Uppsala universitet,Klinisk kemi,Science for Life Laboratory, SciLifeLab,Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA(Swepub:uu)agsie424 (author)
Siegerink, BobCharite, Ctr Stroke Res Berlin, Berlin, Germany. (author)
Soehnlein, OliverKarolinska Institutet (author)
Soriano, Eva MariaUniv Reading, Sch Biol Sci, Inst Cardiovasc & Metab Res, Reading, Berks, England. (author)
Sowa, Marcin A.Univ Reading, Sch Biol Sci, Inst Cardiovasc & Metab Res, Reading, Berks, England. (author)
Spronk, Henri M. H.Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
Storey, Robert F.Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England. (author)
Tantiwong, ChukiatCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands. (author)
Veninga, AliciaCARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.;Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA. (author)
Wang, XueqingUniv Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England. (author)
Watson, Steve P.Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England. (author)
Weitz, JeffUniv Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England.;McMaster Univ, Dept Med, Div Hematol & Thromboembolism, Hamilton, ON, Canada.;McMaster Univ, Thrombosis & Atherosclerosis Res Inst, Hamilton, ON, Canada. (author)
Zeerleder, Sacha S.Univ Bern, Bern Univ Hosp, Inselspital, Dept Haematol, Bern, Switzerland.;Univ Bern, Bern Univ Hosp, Inselspital, Cent Haematol Lab, Bern, Switzerland.;Univ Bern, Dept BioMed Res, Bern, Switzerland. (author)
ten Cate, HugoMaastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. (author)
Lina, Badimon (author)
Christoph, Binder (author)
Marc, Hoylaerts (author)
Peter, Karlheinz (author)
GregoryLip, Koenen Rory (author)
Steffen, Massberg (author)
Philipp, von Hundelshausen (author)
Christian, Weber (author)
Johann, Wojta (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Dermatol, Mainz, Germany. (creator_code:org_t)

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By the author/editor: d'Alessandro, El ...; Becker, Christia ...; Bergmeier, Wolfg ...; Bode, Christoph; Bourne, Joshua H ...; Brown, Helena; show more...; Buller, Harry R.; ten Cate-Hoek, A ...; ten Cate, Vincen ...; van Cauteren, Yv ...; Cheung, Yam F. H ...; Cleuren, Audrey; Coenen, Danielle; Crijns, Harry J. ...; de Simone, Ilari ...; Dolleman, Sophie ...; Klein, Christine ...; Fernandez, Delia ...; Granneman, Liann ...; van t Hof, Arnou ...; Henke, Peter; Henskens, Yvonne ...; Huang, Jingnan; Jennings, Lisa K ...; Jooss, Natalie; Karel, Mieke; van den Kerkhof, ...; Klok, Frederik A ...; Kremers, Bram; Laemmle, Bernhar ...; Leader, Avi; Lundstrom, Annik ...; Mackman, Nigel; Mannucci, Pier M ...; Maqsood, Zahra; van der Meijden, ...; van Moorsel, Mar ...; Moran, Luis A.; Morser, John; van Mourik, Mano ...; Navarro, Stefano; Neagoe, Raluca A ...; Olie, Renske H.; van Paridon, Pau ...; Posma, Jens; Provenzale, Isab ...; Reitsma, Pieter ...; Scaf, Billy; Schurgers, Leon; Seelig, Jaap; Siegbahn, Agneta ...; Siegerink, Bob; Soehnlein, Olive ...; Soriano, Eva Mar ...; Sowa, Marcin A.; Spronk, Henri M. ...; Storey, Robert F ...; Tantiwong, Chuki ...; Veninga, Alicia; Wang, Xueqing; Watson, Steve P.; Weitz, Jeff; Zeerleder, Sacha ...; ten Cate, Hugo; Lina, Badimon; Christoph, Binde ...; Marc, Hoylaerts; Peter, Karlheinz; GregoryLip, Koen ...; Steffen, Massber ...; Philipp, von Hun ...; Christian, Weber; Johann, Wojta; show less...

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