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Effects and moderat...
Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer : Aggregate data and individual patient data meta-analyses
- Article/chapterEnglish2020
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Elsevier BV,2020
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LIBRIS-ID:oai:DiVA.org:uu-418989
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-418989URI
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https://doi.org/10.1016/j.cpr.2020.101882DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:144492358URI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:for swepub-publicationtype
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PURPOSE: This study evaluated the effects of coping skills training (CST) on symptoms of depression and anxiety in cancer patients, and investigated moderators of the effects.METHODS: Overall effects and intervention-related moderators were studied in meta-analyses of pooled aggregate data from 38 randomized controlled trials (RCTs). Patient-related moderators were examined using linear mixed-effect models with interaction tests on pooled individual patient data (n = 1953) from 15 of the RCTs.RESULTS: CST had a statistically significant but small effect on depression (g = -0.31,95% confidence interval (CI) = -0.40;-0.22) and anxiety (g = -0.32,95%CI = -0.41;-0.24) symptoms. Effects on depression symptoms were significantly larger for interventions delivered face-to-face (p = .003), led by a psychologist (p = .02) and targeted to patients with psychological distress (p = .002). Significantly larger reductions in anxiety symptoms were found in younger patients (pinteraction < 0.025), with the largest reductions in patients <50 years (β = -0.31,95%CI = -0.44;-0.18) and no significant effects in patients ≥70 years. Effects of CST on depression (β = -0.16,95%CI = -0.25;-0.07) and anxiety (β = -0.24,95%CI = -0.33;-0.14) symptoms were significant in patients who received chemotherapy but not in patients who did not (pinteraction < 0.05).CONCLUSIONS: CST significantly reduced symptoms of depression and anxiety in cancer patients, and particularly when delivered face-to-face, provided by a psychologist, targeted to patients with psychological distress, and given to patients who were younger and received chemotherapy.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Schreurs, M. A. C.
(author)
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Abrahams, H. J. G.
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Kalter, J.
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Aaronson, N. K.
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Jacobsen, P. B.
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Newton, R. U.
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Courneya, K. S.
(author)
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Armes, J.
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Arving, CeciliaUppsala universitet,Livsstil och rehabilitering vid långvarig sjukdom(Swepub:uu)ceciarvi
(author)
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Braamse, A. M.
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Brandberg, Y.Karolinska Institutet
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Dekker, J.
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Ferguson, R. J.
(author)
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Gielissen, M. F.
(author)
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Glimelius, BengtUppsala universitet,Experimentell och klinisk onkologi(Swepub:uu)bengglim
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Goedendorp, M. M.
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Graves, K. D.
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Heiney, S. P.
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Horne, R.
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Hunter, M. S.
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Johansson, Birgitta,1959-Uppsala universitet,Experimentell och klinisk onkologi,Birgitta Johansson(Swepub:uu)birgjhs
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Northouse, L. L.
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Oldenburg, H. S.
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Prins, J. B.
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Savard, J.
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van Beurden, M.
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van den Berg, S. W.
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Brug, J.
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Knoop, H.
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Verdonck-de Leeuw, I. M.
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Uppsala universitetLivsstil och rehabilitering vid långvarig sjukdom
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In:Clinical Psychology Review: Elsevier BV800272-73581873-7811
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Buffart, L. M.
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Schreurs, M. A. ...
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Abrahams, H. J. ...
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Kalter, J.
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Aaronson, N. K.
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Jacobsen, P. B.
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Newton, R. U.
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Courneya, K. S.
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Armes, J.
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Arving, Cecilia
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Braamse, A. M.
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Brandberg, Y.
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Dekker, J.
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Ferguson, R. J.
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Gielissen, M. F.
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Glimelius, Bengt
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Goedendorp, M. M ...
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Graves, K. D.
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Heiney, S. P.
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Horne, R.
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Hunter, M. S.
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Johansson, Birgi ...
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Northouse, L. L.
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Oldenburg, H. S.
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Prins, J. B.
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Savard, J.
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van Beurden, M.
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van den Berg, S. ...
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Brug, J.
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Knoop, H.
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Verdonck-de Leeu ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Other Health Sci ...
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Clinical Psychol ...
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Uppsala University
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Karolinska Institutet