Chocolate Intake and Incidence of Heart Failure A Population-Based Prospective Study of Middle-Aged and Elderly Women

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Mostofsky, ElizabethHarvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Cardiovasc Epidemiol Res Unit,Dept Med, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. (author)

Chocolate Intake and Incidence of Heart Failure A Population-Based Prospective Study of Middle-Aged and Elderly Women

Article/chapterEnglish2010

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LIPPINCOTT WILLIAMS & WILKINS,2010
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LIBRIS-ID:oai:DiVA.org:uu-422099
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422099URI
https://doi.org/10.1161/CIRCHEARTFAILURE.110.944025DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:121320426URI

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Language:English
Summary in:English

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Background-Randomized clinical trials have shown that chocolate intake reduces systolic and diastolic blood pressure, and observational studies have found an inverse association between chocolate intake and cardiovascular disease. The aim of this study was to investigate the association between chocolate intake and incidence of heart failure (HF). Methods and Results-We conducted a prospective cohort study of 31 823 women aged 48 to 83 years without baseline diabetes or a history of HF or myocardial infarction who were participants in the Swedish Mammography Cohort. In addition to answering health and lifestyle questions, participants completed a food-frequency questionnaire. Women were followed from January 1, 1998, through December 31, 2006, for HF hospitalization or death through the Swedish inpatient and cause-of-death registers. Over 9 years of follow-up, 419 women were hospitalized for incident HF (n=379) or died of HF (n=40). Compared with no regular chocolate intake, the multivariable-adjusted rate ratio of HF was 0.74 (95% CI, 0.58 to 0.95) for women consuming 1 to 3 servings of chocolate per month, 0.68 (95% CI, 0.50 to 0.93) for those consuming 1 to 2 servings per week, 1.09 (95% CI, 0.74 to 1.62) for those consuming 3 to 6 servings per week, and 1.23 (95% CI, 0.73 to 2.08) for those consuming >= 1 servings per day (P=0.0005 for quadratic trend). Conclusions-In this population, moderate habitual chocolate intake was associated with a lower rate of HF hospitalization or death, but the protective association was not observed with intake of >= 1 servings per day. (Circ Heart Fail. 2010;3:612-616.)

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
diet
epidemiology
heart failure

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Levitan, Emily B.Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Cardiovasc Epidemiol Res Unit,Dept Med, Boston, MA 02115 USA. (author)
Wolk, AlicjaKarolinska Institutet (author)
Mittleman, Murray A.Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Cardiovasc Epidemiol Res Unit,Dept Med, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. (author)
Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Cardiovasc Epidemiol Res Unit,Dept Med, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Cardiovasc Epidemiol Res Unit,Dept Med, Boston, MA 02115 USA. (creator_code:org_t)

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In:Circulation Heart Failure: LIPPINCOTT WILLIAMS & WILKINS3:5, s. 612-6161941-32891941-3297

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