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Coffee consumption and risk of myocardial infarction among older Swedish women

Rosner, Sarah A. (author)
Karolinska Institutet
Akesson, Agneta (author)
Karolinska Institutet
Stampfer, Meir J. (author)
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Wolk, Alicja (author)
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 (creator_code:org_t)
2006-11-16
2007
English.
In: American Journal of Epidemiology. - Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Karolinska Inst, Inst Environm Med, Div Nutr Epidemiol, S-10401 Stockholm, Sweden. : OXFORD UNIV PRESS INC. - 0002-9262 .- 1476-6256. ; 165:3, s. 288-293
  • Journal article (peer-reviewed)
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  • Numerous studies have examined the association between coffee consumption and risk of myocardial infarction (MI), but results have been inconsistent. Case-control studies generally suggest a harmful effect of coffee drinking, whereas cohort studies have mostly shown no association. Recent studies found that coffee may lower the risk of diabetes, a major coronary risk factor. The authors prospectively examined the effect of coffee consumption on MI risk in 32,650 older Swedish women, aged 40-74 years, participating in the Swedish Mammography Cohort; 459 cases of MI developed during 165,896 person-years of follow-up from 1997 to 2002. After adjustment for age, coronary heart disease risk factors, and dietary variables, the relative risk of MI associated with drinking >= 5 cups/week versus 0-4 cups/week was 0.68 (95% confidence interval (CI): 0.43, 1.07). The authors observed a nonsignificant trend toward lower risk with higher consumption levels. Compared with that for 0-4 cups/week, the relative risks of MI were 0.84 ( 95% CI: 0.51, 1.38) for 5-7 cups/week, 0.65 ( 95% CI: 0.41, 1.03) for 2-3 cups/day, 0.64 ( 95% CI: 0.39, 1.04) for 4-5 cups/day, and 0.65 ( 95% CI: 0.37, 1.12) for >= 6 cups/day (p-trend = 0.07). Contrary to previous case-control studies, the authors concluded that coffee consumption does not increase MI risk. Coffee consumption of >= 5 cups/week was nonsignificantly inversely associated with MI risk among older Swedish women.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Keyword

coffee
myocardial infarction
Sweden
women

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ref (subject category)
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Rosner, Sarah A.
Akesson, Agneta
Stampfer, Meir J ...
Wolk, Alicja
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MEDICAL AND HEALTH SCIENCES
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Uppsala University
Karolinska Institutet

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