Sökning: onr:"swepub:oai:DiVA.org:uu-422147" > Intake of the major...
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000 | 06463naa a2200649 4500 | |
001 | oai:DiVA.org:uu-422147 | |
003 | SwePub | |
008 | 201013s2006 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:1931357 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4221472 URI |
024 | 7 | a https://doi.org/10.1002/ijc.220762 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19313572 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Koushik, Anita4 aut |
245 | 1 0 | a Intake of the major carotenoids and the risk of epithelial ovarian cancer in a pooled analysis of 10 cohort studies |
264 | c 2006-07-05 | |
264 | 1 | a Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA. Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA 02115 USA. Harvard Univ, Sch Med, Boston, MA 02115 USA. Harvard Univ, Ctr Canc Prevent, Boston, MA 02115 USA. Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA. Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA. Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA. SUNY Buffalo, Dept Social & Prevent Med, Buffalo, NY USA. TNO, Qual Life, Dept Food & Chem Risk Anal, NL-3700 AJ Zeist, Netherlands. Karolinska Inst, Natl Inst Environm Med, Div Nutrit Epidemiol, Stockholm, Sweden. NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA. Amer Canc Soc, Epidemiol & Surveillance Res, Atlanta, GA 30329 USA. Univ Toronto, Fac Med, Dept Publ Hlth Sci, Toronto, ON, Canada. Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA. Maastricht Univ, NUTRIM, Dept Epidemiol, Maastricht, Netherlands.b WILEY,c 2006 |
338 | a print2 rdacarrier | |
520 | a Carotenoids, found in fruits and vegetables, have the potential to protect against cancer because of their properties, including their functions as precursors to vitamin A and as antioxidants. We examined the associations between intakes of alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein/zeaxanthin and lycopene and the risk of invasive epithelial ovarian cancer. The primary data from 10 prospective cohort studies in North America and Europe were analyzed and then pooled. Carotenoid intakes were estimated from a validated food frequency questionnaire administered at baseline in each study. Study-specific relative risks (RR) were estimated using the Cox proportional hazards model and then combined using a random-effects model. Among 521,911 women, 2,012 cases of ovarian cancer occurred during a follow-up of 7-22 years across studies. The major carotenoids were not significantly associated with the risk of ovarian cancer. The pooled multivariate RRs (95% confidence intervals) were 1.00 (0.95-1.05) for a 600 mu g/day increase in alpha-carotene intake, 0.96 (0.93-1.03) for a 2,500 mu g/day increase in beta-carotene intake, 0.99 (0.97-1.02) for a 100 mu g/day increase in beta-cryptoxanthin intake, 0.98 (0.94-1.03) for a 2,500 mu g/day increase in lutein/zeaxanthin intake and 1.01 (0.97-1.05) for a 4,000 mu g/day increase in lycopene intake. These associations did not appreciably differ by study (p-values, tests for between-studies heterogeneity > 0.17). Also, the observed associations did not vary substantially by subgroups of the population or by histological type of ovarian cancer. These results suggest that consumption of the major carotenoids during adulthood does not play a major role in the incidence of ovarian cancer. (c) 2006 Wiley-Liss, Inc. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a ovarian cancer | |
653 | a carotenoids | |
653 | a pooled analysis | |
653 | a meta-analysis | |
653 | a cohort studies | |
700 | 1 | a Hunter, David J.4 aut |
700 | 1 | a Spiegelman, Donna4 aut |
700 | 1 | a Anderson, Kristin E.4 aut |
700 | 1 | a Buring, Julie E.4 aut |
700 | 1 | a Freudenheim, Jo L.4 aut |
700 | 1 | a Goldbohm, R. Alexandra4 aut |
700 | 1 | a Hankinson, Susan E.4 aut |
700 | 1 | a Larsson, Susanna C.u Karolinska Institutet4 aut |
700 | 1 | a Leitzmann, Michael4 aut |
700 | 1 | a Marshall, James R.4 aut |
700 | 1 | a McCullough, Marjorie L.4 aut |
700 | 1 | a Miller, Anthony B.4 aut |
700 | 1 | a Rodriguez, Carmen4 aut |
700 | 1 | a Rohan, Thomas E.4 aut |
700 | 1 | a Ross, Julie A.4 aut |
700 | 1 | a Schatzkin, Arthur4 aut |
700 | 1 | a Schouten, Leo J.4 aut |
700 | 1 | a Willett, Walter C.4 aut |
700 | 1 | a Wolk, Alicjau Karolinska Institutet4 aut |
700 | 1 | a Zhang, Shumin M.4 aut |
700 | 1 | a Smith-Warner, Stephanie A.4 aut |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t International Journal of Cancerd Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA. Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA 02115 USA. Harvard Univ, Sch Med, Boston, MA 02115 USA. Harvard Univ, Ctr Canc Prevent, Boston, MA 02115 USA. Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA. Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA. Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA. SUNY Buffalo, Dept Social & Prevent Med, Buffalo, NY USA. TNO, Qual Life, Dept Food & Chem Risk Anal, NL-3700 AJ Zeist, Netherlands. Karolinska Inst, Natl Inst Environm Med, Div Nutrit Epidemiol, Stockholm, Sweden. NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA. Amer Canc Soc, Epidemiol & Surveillance Res, Atlanta, GA 30329 USA. Univ Toronto, Fac Med, Dept Publ Hlth Sci, Toronto, ON, Canada. Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA. Maastricht Univ, NUTRIM, Dept Epidemiol, Maastricht, Netherlands. : WILEYg 119:9, s. 2148-2154q 119:9<2148-2154x 0020-7136x 1097-0215 |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.22076 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422147 |
856 | 4 8 | u https://doi.org/10.1002/ijc.22076 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1931357 |
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