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Lipidomics Issues o...
Lipidomics Issues on Human Positive ssRNA Virus Infection : An Update
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- Balgoma, David (author)
- Uppsala universitet,Analytisk farmaceutisk kemi
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- Gil-de-Gómez, Luis (author)
- Childrens Hosp Philadelphia, Ctr Childhood Canc Ctr, Colket Translat Res Ctr, 3501 Civ Ctr Blvd Philadelphia, Philadelphia, PA 19104 USA
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- Montero, Olimpio (author)
- CSIC, Boecillos Technol Pk Bur, Av Francisco Valles 8, Boecillo 47151, Spain
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(creator_code:org_t)
- 2020-08-31
- 2020
- English.
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In: Metabolites. - : MDPI AG. - 2218-1989 .- 2218-1989. ; 10:9
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Abstract
Subject headings
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- The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid metabolism, and the role played by diverse lipids in regard to the infection effectiveness. All these aspects have currently been tackled separately as independent issues and focused on the function of proteins. Here, we review the role of cholesterol and other lipids in ssRNA+ infection.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Keyword
- lipidomics
- ssRNA+ virus
- membrane fusion
- lipid metabolism
- cholesterol
- sphingolipids
- phosphatidylinositol
- SARS-CoV
Publication and Content Type
- ref (subject category)
- for (subject category)
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