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A Deep Learning Based Pipeline for Efficient Oral Cancer Screening on Whole Slide Images

Lu, Jiahao (author)
Uppsala universitet,Avdelningen för visuell information och interaktion,Bildanalys och människa-datorinteraktion
Sladoje, Natasa (author)
Uppsala universitet,Avdelningen för visuell information och interaktion,Bildanalys och människa-datorinteraktion
Runow Stark, Christina (author)
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Darai Ramqvist, Eva (author)
Hirsch, Jan-Michaél (author)
Lindblad, Joakim (author)
Uppsala universitet,Bildanalys och människa-datorinteraktion,Avdelningen för visuell information och interaktion
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 (creator_code:org_t)
2020-06-17
2020
English.
In: Image Analysis and Recognition. - Cham : Springer International Publishing. - 9783030505158 - 9783030505165 ; , s. 249-261
  • Conference paper (peer-reviewed)
Abstract Subject headings
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  • Oral cancer incidence is rapidly increasing worldwide. The most important determinant factor in cancer survival is early diagnosis. To facilitate large scale screening, we propose a fully automated pipeline for oral cancer detection on whole slide cytology images. The pipeline consists of fully convolutional regression-based nucleus detection, followed by per-cell focus selection, and CNN based classification. Our novel focus selection step provides fast per-cell focus decisions at human-level accuracy. We demonstrate that the pipeline provides efficient cancer classification of whole slide cytology images, improving over previous results both in terms of accuracy and feasibility. The complete source code is made available as open source (https://github.com/MIDA-group/OralScreen).

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Medical Engineering -- Medical Image Processing (hsv//eng)

Keyword

CNN
Whole slide imaging
Big data
Cytology
Detection
Focus selection
Classification
Datoriserad bildbehandling
Computerized Image Processing

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