Search: onr:"swepub:oai:DiVA.org:uu-441362" >
Antibody Responses ...
Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 in the Serum and Cerebrospinal Fluid of Patients With Coronavirus Disease 2019 and Neurological Symptoms
-
- Cunningham, Janet (author)
- Uppsala universitet,Psykiatri
-
- Virhammar, Johan (author)
- Uppsala universitet,Neurologi
-
- Rönnberg, Bengt (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Uppsala Univ Hosp, Lab Clin Microbiol, Uppsala, Sweden.,Zoonosis Science Center
-
show more...
-
- Castro Dopico, Xaquin (author)
- Karolinska Institutet
-
- Kolstad, Linda (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Zoonosis Science Center
-
- Albinsson, Bo (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Uppsala Univ Hosp, Lab Clin Microbiol, Uppsala, Sweden.,Zoonosis Science Center
-
- Kumlien, Eva (author)
- Uppsala universitet,Neurologi
-
- Nääs, Anja (author)
- Uppsala universitet,Infektionsmedicin
-
- Klang, Andrea (author)
- Uppsala universitet,Rehabiliteringsmedicin
-
- Westman, Gabriel, 1977- (author)
- Uppsala universitet,Infektionsmedicin
-
- Zetterberg, Henrik (author)
- Univ Gothenburg, Dept Psychiat & Neurochem, Inst Neurosci & Physiol, Sahlgrenska Acad, Mölndal, Sweden.;Sahlgrens Univ Hosp, Clin Neurochem Lab, Mölndal, Sweden.;UCL Inst Neurol, Dept Neurodegenerat Dis, Queen Sq, London, England.;UCL, UK Dementia Res Inst, London, England.
-
- Frithiof, Robert (author)
- Uppsala universitet,Anestesiologi och intensivvård
-
- Lundkvist, Åke (author)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Zoonosis Science Center
-
- Karlsson Hedestam, Gunilla B (author)
- Karolinska Institutet
-
- Rostami, Elham, 1979- (author)
- Karolinska Institutet,Uppsala universitet,Neurokirurgi,Karolinska Inst, Dept Neurosci, Stockholm, Sweden.
-
show less...
-
(creator_code:org_t)
- 2021-03-21
- 2022
- English.
-
In: Journal of Infectious Diseases. - : Oxford University Press (OUP). - 0022-1899 .- 1537-6613. ; 225:6, s. 965-970
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://uu.diva-port... (primary) (Raw object)
-
https://academic.oup...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in serum and cerebrospinal fluid (CSF) samples from 16 patients with coronavirus disease 2019 and neurological symptoms were assessed using 2 independent methods. Immunoglobulin G (IgG) specific for the virus spike protein was found in 81% of patients in serum and in 56% in CSF. SARS-CoV-2 IgG in CSF was observed in 2 patients with negative serological findings. Levels of IgG in both serum and CSF were associated with disease severity (P < .05). All patients with elevated markers of central nervous system damage in CSF also had CSF antibodies (P = .002), and CSF antibodies had the highest predictive value for neuronal damage markers of all tested clinical variables.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- COVID-19
- CSF
- IgG
- SARS-CoV-2
- neurological symptoms
- serology
- Infektionssjukdomar
- Infectious Diseases
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Cunningham, Jane ...
-
Virhammar, Johan
-
Rönnberg, Bengt
-
Castro Dopico, X ...
-
Kolstad, Linda
-
Albinsson, Bo
-
show more...
-
Kumlien, Eva
-
Nääs, Anja
-
Klang, Andrea
-
Westman, Gabriel ...
-
Zetterberg, Henr ...
-
Frithiof, Robert
-
Lundkvist, Åke
-
Karlsson Hedesta ...
-
Rostami, Elham, ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Infectious Medic ...
- Articles in the publication
-
Journal of Infec ...
- By the university
-
Uppsala University
-
Karolinska Institutet