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Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge

Ekbom, Emil (author)
Uppsala universitet,Lung- allergi- och sömnforskning
Frithiof, Robert (author)
Uppsala universitet,Anestesiologi och intensivvård
Emilsson, Össur Ingi (author)
Uppsala universitet,Lung- allergi- och sömnforskning
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Larsson, Ing-Marie, 1963- (author)
Uppsala universitet,Anestesiologi och intensivvård
Lipcsey, Miklós (author)
Uppsala universitet,Anestesiologi och intensivvård,Hedenstiernalaboratoriet
Rubertsson, Sten (author)
Uppsala universitet,Anestesiologi och intensivvård
Wallin, Ewa (author)
Uppsala universitet,Anestesiologi och intensivvård
Janson, Christer (author)
Uppsala universitet,Lung- allergi- och sömnforskning
Hultström, Michael, 1978- (author)
Uppsala universitet,Integrativ Fysiologi,Anestesiologi och intensivvård
Malinovschi, Andrei, 1978- (author)
Uppsala universitet,Klinisk fysiologi
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 (creator_code:org_t)
Elsevier, 2021
2021
English.
In: Respiratory Medicine. - : Elsevier. - 0954-6111 .- 1532-3064. ; 182
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52% of the subjects, with reduced DLCO as the main finding. The risk increased with age above 60 years, need for mechanical ventilation and longer ICU stay as well as lower levels of C-reactive protein at admission. This suggests the need of follow-up with pulmonary function testing in intensive-care treated patients.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)

Keyword

COVID-19
Follow up
Lung function
ARDS
Diffusion capacity
ICU treatment

Publication and Content Type

ref (subject category)
art (subject category)

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