onr:"swepub:oai:DiVA.org:uu-447856"
Search: onr:"swepub:oai:DiVA.org:uu-447856" > Age is the most imp...
- 1 of 1
- Previous record
- Next record
- To hitlist
Age is the most important predictor of survival in diffuse large B-cell lymphoma patients achieving event-free survival at 24 months : a Swedish population-based study
-
- Sabaa, Amal Abu (author)
- Uppsala universitet,Experimentell och klinisk onkologi,Centrum för klinisk forskning, Gävleborg
-
- Mörth, Charlott (author)
- Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Experimentell och klinisk onkologi
-
- Hasselblom, Sverker (author)
- Department of Research, Development and Education, Region Halland, Halmstad, Sweden
- show more...
- show less...
- (creator_code:org_t)
- 2021-05-05
- 2021
- English.
- In: British Journal of Haematology. - : John Wiley & Sons. - 0007-1048 .- 1365-2141. ; 193:5, s. 906-914
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Routine follow-up for diffuse large B-cell lymphoma have been shortened to 2 years when event-free survival at 24 months (EFS24) emerged as a new milestone. In the present study, we aimed to determine whether the achievement of this milestone affected overall survival (OS). We compared OS to that of an age- and sex-matched population, analysed other factors governing OS, and reviewed the causes of death. Data were collected from the Swedish Cancer Registry and from individual patient's records. We included 1169 adult patients from five counties between the years 2001 and 2014. The median (range) age was 64·6 (18-91) years, 56·6% were men and the median follow-up was 82·3 months. For early stages, the achievement of EFS12 did not improve OS. More than two-thirds of the patients (n = 837, 71·6%) achieved EFS24, of which 190 (22·7%) died during follow-up. Lymphoma (20%), cardiovascular disease (22·4%) and malignancies (16%) contributed to causes of death. Patients aged <60 years had an OS that matched the standard population. In multivariate analysis, only age >60 years significantly affected OS after EFS24 compared with the standard population. We concluded that follow-up beyond EFS24 should be considered for patients aged >60 years.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Keyword
- DLBCL
- EFS24
- OS¨
- age
- DLBCL
- EFS24
- age
- OS¨
- Hematology
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- British Journal of Haematology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Sabaa, Amal Abu
- Mörth, Charlott
- Hasselblom, Sver ...
- Hedström, Gustaf
- Flogegård, Max
- Stern, Mimmi
- show more...
- Andersson, Per-O ...
- Glimelius, Ingri ...
- Enblad, Gunilla
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Cancer and Oncol ...
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Hematology
- Articles in the publication
- British Journal ...
- By the university
- Uppsala University
- Karolinska Institutet
- University of Gothenburg
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
