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Symptom clusters in...
Symptom clusters in COVID-19 : A potential clinical prediction tool from the COVID Symptom Study app
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- Sudre, C. H. (author)
- School of Biomedical Engineering & Imaging Sciences, King's College London, Westminster Bridge Road, London SE17EH, UK; MRC Unit for Lifelong Health and Ageing at UCL, University College London, London WC1E 7BH, UK; Centre for Medical Image Computing, Department of Computer Science, University College London, London UK
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- Lee, K. A. (author)
- Department of Twin Research and Genetic Epidemiology King's College London, Westminster Bridge Road, London SE17EH, UK
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- Lochlainn, M. N. (author)
- Department of Twin Research and Genetic Epidemiology King's College London, Westminster Bridge Road, London SE17EH, UK
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- Varsavsky, T. (author)
- School of Biomedical Engineering & Imaging Sciences, King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Murray, B. (author)
- School of Biomedical Engineering & Imaging Sciences, King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Graham, M. S. (author)
- School of Biomedical Engineering & Imaging Sciences, King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Menni, C. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Modat, M. (author)
- School of Biomedical Engineering & Imaging Sciences, King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Bowyer, R. C. E. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Nguyen, L. H. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Drew, D. A. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Joshi, A. D. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Ma, W. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Guo, C. G. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Lo, C. H. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Ganesh, S. (author)
- Zoe Global Limited, 164 Westminster Bridge Road, London SE1 7RW, UK
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- Buwe, A. (author)
- Zoe Global Limited, 164 Westminster Bridge Road, London SE1 7RW, UK
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- Pujol, J. C. (author)
- Zoe Global Limited, 164 Westminster Bridge Road, London SE1 7RW, UK
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- du Cadet, J. L. (author)
- Zoe Global Limited, 164 Westminster Bridge Road, London SE1 7RW, UK
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- Visconti, A. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Freidin, M. B. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- El-Sayed Moustafa, J. S. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Gomez, Maria F. (author)
- Lund University,Lunds universitet,Diabetiska komplikationer,Forskargrupper vid Lunds universitet,Diabetic Complications,Lund University Research Groups
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- Davies, R. (author)
- Zoe Global Limited, 164 Westminster Bridge Road, London SE1 7RW, UK
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- Gomez, M. F. (author)
- Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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- Fall, Tove, 1979- (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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- Cardoso, M. J. (author)
- School of Biomedical Engineering & Imaging Sciences, King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Wolf, J. (author)
- Zoe Global Limited, 164 Westminster Bridge Road, London SE1 7RW, UK
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- Franks, Paul W. (author)
- Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,King's College London
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- Chan, A. T. (author)
- Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, USA
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- Spector, T. D. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Steves, C. J. (author)
- Department of Twin Research and Genetic Epidemiology King’s College London, Westminster Bridge Road, London SE17EH, UK
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- Ourselin, S. (author)
- School of Biomedical Engineering & Imaging Sciences, King’s College London, Westminster Bridge Road, London SE17EH, UK
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(creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2021
- 2021
- English.
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In: Science Advances. - : American Association for the Advancement of Science (AAAS). - 2375-2548. ; 7:12
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
Close
- As no one symptom can predict disease severity or the need for dedicated medical support in coronavirus disease 2019 (COVID-19), we asked whether documenting symptom time series over the first few days informs outcome. Unsupervised time series clustering over symptom presentation was performed on data collected from a training dataset of completed cases enlisted early from the COVID Symptom Study Smartphone application, yielding six distinct symptom presenta- tions. Clustering was validated on an independent replication dataset between 1 and 28 May 2020. Using the first 5 days of symptom logging, the ROC-AUC (receiver operating characteristic – area under the curve) of need for respiratory sup- port was 78.8%, substantially outperforming personal characteristics alone (ROC-AUC 69.5%). Such an approach could be used to monitor at-risk patients and predict medical resource requirements days before they are required.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- COVID-19
- COVID Symptom Study app
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
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Sudre, C. H.
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Lee, K. A.
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Lochlainn, M. N.
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Varsavsky, T.
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Murray, B.
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Graham, M. S.
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show more...
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Menni, C.
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Modat, M.
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Bowyer, R. C. E.
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Nguyen, L. H.
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Drew, D. A.
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Joshi, A. D.
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Ma, W.
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Guo, C. G.
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Lo, C. H.
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Ganesh, S.
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Buwe, A.
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Pujol, J. C.
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du Cadet, J. L.
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Visconti, A.
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Freidin, M. B.
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El-Sayed Moustaf ...
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Gomez, Maria F.
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Davies, R.
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Gomez, M. F.
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Fall, Tove, 1979 ...
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Cardoso, M. J.
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Wolf, J.
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Franks, Paul W.
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Chan, A. T.
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Spector, T. D.
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Steves, C. J.
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Ourselin, S.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
- Articles in the publication
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Science Advances
- By the university
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Uppsala University
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Lund University