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Results of renal ar...
Results of renal artery revascularization in the post-ASTRAL era with 4 years mean follow-up
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- Zachrisson, Karin (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology
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- Krupic, Ferid (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics
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- Svensson, Mikael, 1980 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Wigelius, Ann (author)
- Umeå Univ Hosp, Dept Radiat Sci, Diagnost Radiol, Umeå, Sweden.
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- Jonsson, Andreas (author)
- Umeå Univ Hosp, Dept Publ Hlth & Clin Med, Umeå, Sweden.
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- Dimopoulou, Angeliki, 1975- (author)
- Uppsala universitet,Radiologi
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- Stenborg, Anna (author)
- Uppsala universitet,Klinisk epidemiologi
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- Jensen, Gert, 1950 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Herlitz, Hans, 1946 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Gottsäter, Anders (author)
- Skane Univ Hosp, Vasc Ctr, Clin Vasc Dis Res, Malmö, Sweden.
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- Falkenberg, Mårten, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology
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(creator_code:org_t)
- 2020-05-02
- 2020
- English.
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In: Blood Pressure. - : TAYLOR & FRANCIS LTD. - 0803-7051 .- 1651-1999. ; 29:5, s. 285-290
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https://doi.org/10.1...
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Abstract
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- Purpose: To investigate contemporary results of percutaneous transluminal renal angioplasty (PTRA).Materials and Methods: A multicentre retrospective study analysing all patients treated with PTRA for primary symptomatic renal artery stenosis (RAS) between 2010 and 2013 at four tertiary centres. Procedures during the preceding four years were counted to evaluate for change in PTRA frequency.Results: The number of PTRA procedures decreased by approximately 50% from 2006 to 2013. Patients treated in the post-ASTRAL period (n = 224) had a significant reduction in mean systolic pressure (168 to 146 mmHg, p < 0.01), diastolic pressure (84 to 76 mmHg, p < 0.01), number of anti-hypertensive drugs (3.54 to 3.05, p < 0.01), and anti-hypertensive treatment index (21.75 to 16.92, p < 0.01) compared to before PTRA. These improvements were maintained at one year and at the last clinical evaluation after a mean follow-up of 4.31 years. Renal function increased transiently without sustained improvement, or deterioration, during later follow-up. Thirteen patients (5.8%) eventually required dialysis, nine of these had eGFR <20 ml/min/1.73 m2 before PTRA. There was no difference in outcomes between subgroups differentiated by different indications for PTRA.Conclusion: The frequency of PTRA has decreased, indicating a higher threshold for invasive treatment of RAS in recent years. The reduction in blood pressures, the reduced need for anti-hypertensive medication, and stabilization of renal function over time suggest a clinical benefit for most patients who are now being treated with PTRA.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
Keyword
- Hypertension
- percutaneous transluminal renal angioplasty
- PTRA
- renal artery stenosis
- renal insufficiency
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Zachrisson, Kari ...
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Krupic, Ferid
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Svensson, Mikael ...
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Wigelius, Ann
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Jonsson, Andreas
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Dimopoulou, Ange ...
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Stenborg, Anna
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Jensen, Gert, 19 ...
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Herlitz, Hans, 1 ...
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Gottsäter, Ander ...
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Falkenberg, Mårt ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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MEDICAL AND HEAL ...
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and Health Sciences
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- Articles in the publication
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Blood Pressure
- By the university
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Uppsala University
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University of Gothenburg